Spinal Fusion Clinical Trials

28 recruitingLast updated: May 13, 2026

There are 28 actively recruiting spinal fusion clinical trials across 18 countries. Studies span Not Applicable, Phase 4, Phase 2, Early Phase 1, Phase 3. Top locations include New York, New York, United States, St Louis, Missouri, United States, San Francisco, California, United States. Updated daily from ClinicalTrials.gov.


Spinal Fusion Trials at a Glance

28 actively recruiting trials for spinal fusion are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 14 trials, with the heaviest enrollment activity in New York, St Louis, and San Francisco. Lead sponsors running spinal fusion studies include Columbia University, Medtronic Spinal and Biologics, and Alexander T. Yahanda.

Browse spinal fusion trials by phase

Treatments under study

About Spinal Fusion Clinical Trials

Looking for clinical trials for Spinal Fusion? There are currently 21 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Spinal Fusion trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Spinal Fusion clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 28 trials

Recruiting
Not Applicable

The Ailliance Post-Market Clinical Study

Spinal DeformitySpinal Degenerative DisorderSpinal Fusion Failure+2 more
Medtronic Spinal and Biologics1,000 enrolled26 locationsNCT05856370
Recruiting
Phase 2

Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

AnesthesiaSpinal FusionNausea and Vomiting, Postoperative
IWK Health Centre100 enrolled1 locationNCT06357234
Recruiting
Not Applicable

PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery.

Postoperative PainSurgical Blood LossLumbar Spinal Fusion Surgery
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau62 enrolled2 locationsNCT07550114
Recruiting
Early Phase 1

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

DeliriumPain, BackSpinal Fusion+1 more
University of Iowa50 enrolled1 locationNCT05461092
Recruiting

Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

Spinal Fusion
AO Foundation, AO Spine1,244 enrolled17 locationsNCT06368245
Recruiting
Not Applicable

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

Spinal fusion surgeryPostoperative Pain ManagementSpine Fusion+9 more
Alexander T. Yahanda50 enrolled1 locationNCT07218133
Recruiting
Not Applicable

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

Chronic Lower Back PainSpinal Fusion
University of California, Los Angeles80 enrolled2 locationsNCT06282770
Recruiting
Early Phase 1

Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery

Open Posterior Thoracolumbar Spinal Fusion Procedure
Rush University Medical Center604 enrolled1 locationNCT03849443
Recruiting
Not Applicable

Analgesic Efficacy of Multiple Mid-Transverse Process to Pleura (MTP) Block and PCA in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion

PCAIdiopathic ScoliosisMultiple Mid-Transverse Process to Pleura+1 more
Tanta University40 enrolled1 locationNCT06820190
Recruiting
Phase 4

Ketorolac Effects on Post-operative Pain and Lumbar Fusion

Lumbar Spinal Fusion
University of Maryland St. Joseph Medical Center140 enrolled1 locationNCT06513208
Recruiting
Not Applicable

Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis

Spinal StenosisLumbar Spinal StenosisSpinal Fusion
Sklifosovsky Institute of Emergency Care86 enrolled2 locationsNCT05273879
Recruiting
Not Applicable

Erector Spinae Plane Block in Lumbar Spinal Fusion

Lumbar Spinal Fusion
Clinique Saint Jean, France130 enrolled1 locationNCT04904575
Recruiting
Phase 2Phase 3

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

Surgery--ComplicationsIron-deficiencySpinal Fusion+4 more
Columbia University120 enrolled1 locationNCT07217873
Recruiting
Not Applicable

Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine

Post Operative PainSpinal Fusion
Boston Children's Hospital128 enrolled1 locationNCT06471348
Recruiting
Not Applicable

Kids With Iron Deficiency and Scoliosis

Perioperative/Postoperative ComplicationsAdolescent Idiopathic ScoliosisIron Deficiencies+4 more
Columbia University275 enrolled1 locationNCT06042699
Recruiting
Phase 2

Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery

Spinal Fusion
Hospital for Special Surgery, New York96 enrolled1 locationNCT03841058
Recruiting
Not Applicable

Pulse-Width Modulation

Spinal StenosisSpinal Fusion
Dartmouth-Hitchcock Medical Center50 enrolled1 locationNCT06120231
Recruiting
Phase 3

A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

Postoperative PainPostoperative DeliriumSpinal Fusion
University of California, San Francisco278 enrolled1 locationNCT05010148
Recruiting

A Post Market Surveillance on INFUSE Bone Graft

Intervertebral disc degenerationSpinal FusionLumbar Disc Disease
Medtronic Spinal and Biologics600 enrolled1 locationNCT05299762
Recruiting
Phase 4

Safety and Efficacy of Subdermal Betadine During Posterior Spinal Fusion

Spinal Fusion
Akron Children's Hospital60 enrolled1 locationNCT06744907