Stress Reaction Clinical Trials

13 recruitingLast updated: May 13, 2026

There are 13 actively recruiting stress reaction clinical trials across 3 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4. Top locations include St Louis, Missouri, United States, Camden, New Jersey, United States, Bethesda, Maryland, United States. Updated daily from ClinicalTrials.gov.


Stress Reaction Trials at a Glance

13 actively recruiting trials for stress reaction are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in St Louis, Camden, and Bethesda. Lead sponsors running stress reaction studies include University of North Carolina, Chapel Hill, Charlotte Tate, and Charite University, Berlin, Germany.

Browse stress reaction trials by phase

Treatments under study

About Stress Reaction Clinical Trials

Looking for clinical trials for Stress Reaction? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Stress Reaction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Stress Reaction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Phase 1Phase 2

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Quality of LifeDepression, AnxietyStress Reaction+1 more
Children's Hospital Los Angeles66 enrolled1 locationNCT05685368
Recruiting
Not Applicable

Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress Test

healthy adult participantsHealthyAcute Stress Reaction+1 more
Medical University of Bialystok120 enrolled1 locationNCT07529379
Recruiting
Phase 2

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

Neurocognitive FunctionPost-traumatic StressAcute Stress Disorder+1 more
University of North Carolina, Chapel Hill180 enrolled9 locationsNCT06636786
Recruiting
Phase 2

BXCL501 After Stress to Increase Recovery Success

Post Traumatic Stress DisorderAcute Stress DisorderAcute Stress Reaction
University of North Carolina, Chapel Hill100 enrolled3 locationsNCT06943404
Recruiting
Not Applicable

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

Sleep DisturbancePTSDEmotional Regulation+12 more
Walter Reed National Military Medical Center40 enrolled2 locationsNCT05414708
Recruiting
Not Applicable

Promoting Improved Functioning Among People Experiencing Stressful Situations

Acute Stress Reaction
University of North Carolina, Chapel Hill450 enrolled5 locationsNCT06482567
Recruiting
Not Applicable

Self-Management Interventions After an ICD Shock

PTSDImplantable Defibrillator UserStress Reaction+2 more
University of Washington60 enrolled1 locationNCT06037785
Recruiting
Phase 4

The Effects of Propranolol, Hydrocortisone, and Morphine on Military-Relevant Performance Outcomes

Acute Stress ReactionFear of Spiders
Walter Reed Army Institute of Research (WRAIR)110 enrolled1 locationNCT06982183
Recruiting
Not Applicable

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

StressAcute Stress ReactionCBD+1 more
University of Minnesota125 enrolled1 locationNCT07069478
Recruiting
Not Applicable

Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder

RelapseAlcohol Use DisorderRisk Behavior+4 more
Central Institute of Mental Health, Mannheim100 enrolled2 locationsNCT06105853
Recruiting

Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer

StressSmoking, TobaccoAlcoholism+3 more
Charite University, Berlin, Germany300 enrolled2 locationsNCT05992272
Recruiting
Not Applicable

Bilateral Infant Stimulation Study

Preterm BirthParent-Child RelationsStress Reaction+1 more
Oregon Health and Science University40 enrolled1 locationNCT06353243
Recruiting
Phase 1

Biological and Behavioral Outcomes of Community Nature Walks

Stress, PsychologicalStress ReactionTelomere Shortening
Charlotte Tate200 enrolled1 locationNCT06056375