Phase 4 Stress Clinical Trials

45 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 45 trials

Recruiting
Phase 4

The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response

surgical stress responseThyroid CancerThyroid and Parathyroid Surgery+1 more
University Hospital Dubrava48 enrolled1 locationNCT07600580
Recruiting
Phase 4

Computational Assessment of GABA Receptor Modulation in PTSD

Stress Disorders, Post-Traumatic
VA Office of Research and Development150 enrolled1 locationNCT06852469
Recruiting
Phase 4

Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial

DexmedetomidineLignocaineLaryngoscopic Stress Response
Rawalpindi Institute of Cardiology70 enrolled1 locationNCT07611890
Recruiting
Phase 4

Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 Minutes

Cerebral oxygen saturationInfant Respiratory Distress SyndromeCerebral Oxygenation+3 more
Medical University of Graz76 enrolled1 locationNCT07261787
Recruiting
Phase 4

The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes

Acute Stress ReactionFear of Spiders
Walter Reed Army Institute of Research (WRAIR)88 enrolled1 locationNCT06982183
Recruiting
Phase 4

Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery

Stress Disorders, Post-Traumatic
Massachusetts General Hospital80 enrolled1 locationNCT05853627
Recruiting
Phase 4

Calfactant vs Poractant Alfa Using a Less Invasive Technique in Preterm Infants With Respiratory Distress Syndrome

SurfactantRespiratory Distress Syndrome in Premature InfantsRespiratory Distress Syndrome (RDS)
Uludag University234 enrolled5 locationsNCT07350018
Recruiting
Phase 4

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

surgical stress responsePostoperative FatiguePostoperative Sleep Disturbances
Ziekenhuis Oost-Limburg102 enrolled1 locationNCT06480539
Recruiting
Phase 4

Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa

Premature BirthRespiratory Distress Syndrome in Premature InfantSurfactant Deficiency Syndrome Neonatal+1 more
Indiana University1,512 enrolled8 locationsNCT06554522
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 4

Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints

Posttraumatic Stress Disorder (PTSD)
VA Office of Research and Development70 enrolled3 locationsNCT05776056
Recruiting
Phase 4

Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder

Post Traumatic Stress Disorder
NYU Langone Health80 enrolled1 locationNCT05391971
Not Yet Recruiting
Phase 4

Immune Effects of Respiratory Syncytial Virus (RSV) Vaccination in Older Adults

Response to vaccinationDepressionStress+1 more
Tasmanian Health Service120 enrolled1 locationACTRN12625001211459
Recruiting
Phase 4

Aging, Beta Blockers, and Thermoregulatory Responses

AgingHeat Stress
University of Texas Southwestern Medical Center22 enrolled1 locationNCT06582680
Recruiting
Phase 4

Assessing the Utility of Prophylactic Antibiotics at Time of Urethral Bulking Using Bulkamid (Bulkamid Study)

Stress Urinary Incontinence
Ohio State University138 enrolled1 locationNCT06706362
Recruiting
Phase 4

Non Inferiority Trial Investigating Surfactants Administered Via MIST

Respiratory distress syndrome
Endeavor Health262 enrolled1 locationNCT06074380
Recruiting
Phase 4

Prophylactic Minimally Invasive Surfactant Evaluation

Premature BirthRespiratory Distress Syndrome, Newborn
Endeavor Health200 enrolled1 locationNCT06007547
Recruiting
Phase 4

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

Sleep Initiation and Maintenance DisordersStress Disorders, Posttraumatic
VA Office of Research and Development190 enrolled4 locationsNCT03642028
Recruiting
Phase 4

Misoprostol Before Caesarean Section

Caesarean SectionMisoprostolRespiratory Distress Syndrome (RDS) of Neonate
Kafrelsheikh University160 enrolled1 locationNCT06946914
Recruiting
Phase 4

Treatment of ARDS With Sivelestat Sodium

Acute Respiratory Distress Syndrome
Sichuan Provincial People's Hospital324 enrolled1 locationNCT04909697