Phase 1 Stress Clinical Trials
26 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 26 trials
Recruiting
Phase 1Phase 2
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting
Phase 1Phase 2
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmCOVID-19 Infection+2 more
M.D. Anderson Cancer Center70 enrolled1 locationNCT04565665
Recruiting
Phase 1Phase 2
Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
Quality of LifeDepression, AnxietyStress Reaction+1 more
Children's Hospital Los Angeles66 enrolled1 locationNCT05685368
Recruiting
Phase 1Phase 2
Mesenchymal Stem Cells (MSCs) and Conditioned Medium Mesenchymal Stem Cells as Adjuvant Therapy for Sepsis
Acute Respiratory Distress Syndrome
PT. Prodia Stem Cell Indonesia15 enrolled1 locationNCT07439848
Recruiting
Phase 1Phase 2
A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Changchun Tuohua Pharmaceutical Co., Ltd.36 enrolled1 locationNCT07413978
Recruiting
Phase 1
A Dose Escalation Study of NanO2 in Patients With Mild Respiratory Distress
Mild Respiratory Distress
NuvOx LLC18 enrolled2 locationsNCT06658535
Recruiting
Phase 1Phase 2
Mitigating PTSD-CUD After Sexual Assault
Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841
Recruiting
Phase 1
Inflammatory Challenge and Fear
Posttraumatic Stress Disorder (PTSD)
University of California, San Francisco288 enrolled1 locationNCT06630884
Recruiting
Phase 1Phase 2
Study of Cannabidiol and Neuroimaging on Stress
StressTraumaEarly Life Adversity
Icahn School of Medicine at Mount Sinai160 enrolled1 locationNCT07278505
Recruiting
Phase 1
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance10 enrolled1 locationNCT06335407
Recruiting
Phase 1
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
Posttraumatic Stress Disorder
Johns Hopkins University40 enrolled1 locationNCT06989957
Not Yet Recruiting
Phase 1
Testing the Safety and Effects of the Psychedelic Psilocin on Wellbeing and Anxiety in People with Ongoing Physical and Mental Health Conditions
Chronic Fatigue SyndromeAnorexia NervosaFibromyalgia+6 more
Tryptamine Therapeutics66 enrolled1 locationACTRN12625000949482
Recruiting
Phase 1
Effects of Cannabidiol on Stress and Nicotine Withdrawal
StressNicotine DependenceTobacco Smoking+1 more
Johns Hopkins University90 enrolled1 locationNCT07001930
Recruiting
Phase 1
Alexithymia Intervention for Suicide
SchizophreniaPost Traumatic Stress DisorderSuicide+2 more
VA Office of Research and Development40 enrolled1 locationNCT05724953
Recruiting
Phase 1
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Post Traumatic Stress DisorderDepressive Disorder, Major
Yale University50 enrolled1 locationNCT05915013
Recruiting
Phase 1
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
StressStress (Psychology)Stress, Psychologic+4 more
Center for Advanced Facial Plastic Surgery20 enrolled1 locationNCT06778421
Recruiting
Phase 1Phase 2
PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)
Depression, AnxietyDistress, Emotional
Ottawa Hospital Research Institute20 enrolled2 locationsNCT04754061
Recruiting
Phase 1
Differences by Sex and Genotype in the Effects of Stress on Executive Functions
Stress
University of British Columbia146 enrolled1 locationNCT04273880
Recruiting
Phase 1
Biological and Behavioral Outcomes of Community Nature Walks
Stress, PsychologicalStress ReactionTelomere Shortening
Charlotte Tate200 enrolled1 locationNCT06056375
Completed
Phase 1
The effect of a dietary ketone on immunity, tolerability and performance in well-trained, healthy male cyclists.
Systemic symptoms (e.g. dizziness, nausea)Exercise-Induced immunosuppressionGastrointestinal distress
Auckland University of Technology12 enrolled1 locationACTRN12617001347358