Phase 4 Symptom Clinical Trials

24 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 24 trials

Recruiting
Phase 4

Comparison of Ocular Lubricants in People With Symptoms of Dry Eye

Dry Eye Symptoms
University of Waterloo100 enrolled1 locationNCT07451184
Recruiting
Phase 4

Pectoral Block in Breast Reduction for Pain Control

Macromastia (Symptomatic)
Carilion Clinic80 enrolled1 locationNCT07527039
Recruiting
Phase 4

Intraoral Cryotherapy on Anesthetic Efficacy in Mandibular Incisors

Symptomatic Irreversible Pulpitis (SIP)
Ondokuz Mayıs University98 enrolled1 locationNCT07517367
Recruiting
Phase 4

A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb50 enrolled31 locationsNCT07004972
Recruiting
Phase 4

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4

Nasal Antisepsis for C. Auris Prevention

Candida Auris InfectionColonization, Asymptomatic
Mary K Hayden120 enrolled3 locationsNCT06282510
Recruiting
Phase 4

Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder

Somatic Symptom Disorder (DSM-V)
All India Institute of Medical Sciences, Bhubaneswar84 enrolled1 locationNCT06803485
Recruiting
Phase 4

Imaging Biomarkers of FOG Response to DBS

Deep Brain StimulationFreezing of Gait Symptoms in Parkinson's Disease
Medical University of South Carolina54 enrolled1 locationNCT06951906
Recruiting
Phase 4

Decolonization Efficacy of Polyhexanide vs. Mupirocin

Staphylococcus AureusColonization, Asymptomatic
Swiss Paraplegic Research, Nottwil24 enrolled1 locationNCT06633588
Recruiting
Phase 4

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

AnxietyDepressive Symptoms
University of Cincinnati60 enrolled1 locationNCT04245436
Recruiting
Phase 4

The Efficacy and Safety of Silodosin Singly or Combined With Ningmitai Capsules in the Treatment of Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Xintian Pharmaceutical312 enrolled8 locationsNCT05551221
Completed
Phase 4

To check the efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis after premedication with ketorolac and diclofenac potassium

Symptomatic Irreversible Pulpitis
Dr. Sara Bano130 enrolled1 locationACTRN12622000633785
Recruiting
Phase 4

Transcatheter Aortic Valve Replacement Single Center Registry in Chinese Population

Symptomatic Aortic Stenosis
Second Affiliated Hospital, School of Medicine, Zhejiang University2,000 enrolled1 locationNCT02803294
Recruiting
Phase 4

Investigating the influence of methylphenidate on perceptual decisions in healthy, young adults

Symptoms of hyperactivitySymptoms of inattention
Monash University35 enrolled1 locationACTRN12619001752156
Recruiting
Phase 4

Optimizing Pain Control in Transurethral Resection of the Prostate

PainBPH With Urinary ObstructionBPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
Benaroya Research Institute50 enrolled1 locationNCT04102566
Not Yet Recruiting
Phase 4

The Effect of vaginal Bromocriptine in controlling Adenomyosis symptoms

symptomatic adenomyosis
Nahed ezzat allam68 enrolled1 locationACTRN12617001122347
Not Yet Recruiting
Phase 4

Comparing a-blocker against combination therapy, a-blocker plus Prostenoa, for male non-neurogenic lower urinary tract symptoms treatment.

Non-neurogenic lower urinary tract symptoms in males
University of Thessaly200 enrolled1 locationACTRN12616001348448
Not Yet Recruiting
Phase 3Phase 4

Role of probiotics in improving post-colonoscopy symptoms and earlier return of normal bowel function

Time taken for bowel function to return to normal after colonoscopySymptoms after colonoscopy (abdominal pain)
Dr Timothy Slack200 enrolled1 locationACTRN12612000377831
Completed
Phase 4

Does a continuous low-dose antibiotic treatment lower the rates of urinary tract infections and stent related symptoms in patients with ureteral stents compared to a periinterventionel prophylaxis only?

Urinary tract infection (UTI)Ureteral stent related symptoms (SRS)
Department of Urology, University Hospital Bern88 enrolled1 locationACTRN12612000002886
Recruiting
Phase 4

A multi-center, prospective, randomised controlled trial comparing the efficacy and safety of PRODISC-C implant to anterior cervical discectomy and fusion (ACDF) surgery, in the treatment of symptomatic cervical disc disease (SCDD)

Symptomatic cervical disc disease (SCDD)
Synthes Asia Pacific300 enrolled5 locationsACTRN12611000646943