Temporal Lobe Epilepsy Clinical Trials

10 recruitingLast updated: May 21, 2026

There are 10 actively recruiting temporal lobe epilepsy clinical trials across 4 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3. Top locations include Lebanon, New Hampshire, United States, Marseille, France, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Temporal Lobe Epilepsy Trials at a Glance

10 actively recruiting trials for temporal lobe epilepsy are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Lebanon, Marseille, and Boston. Lead sponsors running temporal lobe epilepsy studies include Assistance Publique Hopitaux De Marseille, Genovate-NaviFUS (Australia) Pty Ltd, and Beijing Tiantan Hospital.

Browse temporal lobe epilepsy trials by phase

About Temporal Lobe Epilepsy Clinical Trials

Looking for clinical trials for Temporal Lobe Epilepsy? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Temporal Lobe Epilepsy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Temporal Lobe Epilepsy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

Spatial Scene Recognition Memory in Epilepsy Surgery

Medically refractory epilepsyMemory deficitsMemory Disorders+9 more
University of California, Davis620 enrolled2 locationsNCT07580183
Recruiting

Changes in Attentional Control After a Focal Seizure.

Temporal Lobe EpilepsyFrontal Lobe EpilepsyOthers Subtypes
University Hospital, Lille100 enrolled1 locationNCT06466681
Recruiting
Not Applicable

PRIME: PReservIng Memory in Epilepsy

Mesial Temporal Lobe Epilepsy
Nitin Tandon8 enrolled2 locationsNCT05608408
Recruiting
Phase 1Phase 2

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.12 enrolled18 locationsNCT06063850
Recruiting
Phase 3

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

Mesial Temporal Lobe Epilepsy
Neurona Therapeutics88 enrolled33 locationsNCT05135091
Recruiting
Not Applicable

MRgLITT for mTLE: A PROBE Trial

Temporal Lobe Epilepsy (TLE)
Beijing Tiantan Hospital120 enrolled1 locationNCT06720922
Recruiting

Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging

EpilepsyMultiple SclerosisAlzheimer Disease+7 more
Assistance Publique Hopitaux De Marseille700 enrolled1 locationNCT07202494
Recruiting
Not Applicable

Transcranial Electrical Stimulation Targeting the Cerebellum for the Treatment of Refractory Temporal Lobe Epilepsy

Magnetic Resonance ImagingTemporal Lobe EpilepsyElectroencephalogram+1 more
Xijing Hospital60 enrolled1 locationNCT06558890
Recruiting
Not Applicable

Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy

EpilepsyTemporal Lobe EpilepsyAnomia
Assistance Publique Hopitaux De Marseille214 enrolled12 locationsNCT05609084
Recruiting

Evaluation of the NaviFUS System in drug resistant epilepsy

Drug Resistant Temporal Lobe EpilepsyTemporal Lobe Epilepsy
Genovate-NaviFUS (Australia) Pty Ltd18 enrolled1 locationACTRN12623000382673