Phase 1 Thyroid Clinical Trials
27 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 27 trials
Recruiting
Phase 1Phase 2
Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors
Cervical CancerMelanomaBladder Cancer+6 more
University of Arizona30 enrolled2 locationsNCT06814496
Recruiting
Phase 1
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
MelanomaThyroid CancerGlioma
Pfizer124 enrolled77 locationsNCT05538130
Recruiting
Phase 1Phase 2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Non-small Cell Lung CancerMetastatic Lung CancerMetastatic Lung Non-Small Cell Carcinoma+18 more
Institut de Recherches Internationales Servier554 enrolled11 locationsNCT05786924
Recruiting
Phase 1
Lesion Dosimetry With Iodine-124 in Metastatic Thyroid Carcinoma
Thyroid CarcinomaMetastatic Thyroid Carcinoma
Memorial Sloan Kettering Cancer Center60 enrolled1 locationNCT03647358
Recruiting
Phase 1Phase 2
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Thyroid Eye Disease
Amgen88 enrolled30 locationsNCT06401044
Recruiting
Phase 1Phase 2
Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism
Hypoparathyroidism
Peking Union Medical College Hospital15 enrolled1 locationNCT07530705
Recruiting
Phase 1
Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer
Thyroid Gland Anaplastic CarcinomaBRAF NP_004324.2:p.V600EBRAF V600K Mutation Present
City of Hope Medical Center6 enrolled3 locationsNCT03975231
Recruiting
Phase 1
Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors
Breast CancerHead and Neck Squamous Cell CarcinomaMetastatic Malignant Solid Neoplasm+14 more
Anusha Kalbasi18 enrolled3 locationsNCT04119024
Recruiting
Phase 1Phase 2
Parathyroid Allotransplant for Treatment of Hypoparathyroidism
HypoparathyroidismHypoparathyroidism Post-surgicalHypoparathyroidism Postprocedural
Peter Stock3 enrolled1 locationNCT06961071
Recruiting
Phase 1Phase 2
Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor
Lung CancerPancreas CancerThyroid Cancer+1 more
Sichuan Enray Pharmaceutical Sciences Company54 enrolled9 locationsNCT07433283
Recruiting
Phase 1
177Lu-CTR-FAPI for the Treatment of Thyroid Cancer
Thyroid Cancer
SHAOYAN LIU12 enrolled2 locationsNCT07438847
Recruiting
Phase 1
A Study of GenSci098 in Subjects With Active Thyroid Eye Disease
SafetyTolerabilityGenSci098+1 more
Changchun GeneScience Pharmaceutical Co., Ltd.76 enrolled1 locationNCT06569758
Recruiting
Phase 1Phase 2
Clinical Application of Al18F-NOTA-FAPI-04 PET/CT or PET/MRI Imaging in Malignant Tumor,Cardiovascular or Immune Disease
Malignant TumorHyperthyroidism, AutoimmuneCardiovascular Abnormalities
Peking Union Medical College Hospital600 enrolled1 locationNCT07400224
Recruiting
Phase 1
SLV-154 Treatment of Metastatic Solid Tumors
Breast Cancer MetastaticOvarian CancerEndometrial Cancer+7 more
Solve Therapeutics70 enrolled9 locationsNCT06771219
Recruiting
Phase 1
A Phase I Trial of Af-001 in Patients With Differentiated Thyroid Cancer
DTC - Differentiated Thyroid Cancer
Alpha Fusion Inc.38 enrolled1 locationNCT07287748
Recruiting
Phase 1
A Mass Balance Study of [14C] MT1013 in Hemodialysis Subjects With Secondary Hyperparathyroidism
Hemodialysis Subjects With Secondary Hyperparathyroidism
Shaanxi Micot Pharmaceutical Technology Co., Ltd.6 enrolled1 locationNCT07284043
Recruiting
Phase 1
An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy
Thyroid Gland Carcinoma
M.D. Anderson Cancer Center42 enrolled1 locationNCT04589624
Recruiting
Phase 1
Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting
Phase 1
XL092 and Cemiplimab in BRAF WT Thyroid Cancer
Thyroid CancerBRAF Mutation-Related TumorsAnaplastic Thyroid Cancer
UNC Lineberger Comprehensive Cancer Center12 enrolled2 locationsNCT06902376
Recruiting
Phase 1
CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors
Ovarian CancerCervical CancerLung Cancer+3 more
Chongqing Precision Biotech Co., Ltd90 enrolled1 locationNCT07181720