Phase 1 Thyroid Clinical Trials
30 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 30 trials
Recruiting
Phase 1
Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting
Phase 1Phase 2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Colorectal, CancerColorectal CarcinomaNon-small Cell Lung Cancer+29 more
Institut de Recherches Internationales Servier554 enrolled27 locationsNCT05786924
Recruiting
Phase 1Phase 2
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Thyroid Eye Disease
Amgen88 enrolled38 locationsNCT06401044
Recruiting
Phase 1
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
MelanomaNon-small Cell Lung CancerThyroid Cancer+10 more
Pfizer124 enrolled82 locationsNCT05538130
Recruiting
Phase 1
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
MelanomaNon-small Cell Lung CancerThyroid Cancer+2 more
Pfizer267 enrolled40 locationsNCT05355701
Recruiting
Phase 1Phase 2
Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors
Cervical CancerMelanomaNon-small Cell Lung Cancer+8 more
University of Arizona30 enrolled2 locationsNCT06814496
Recruiting
Phase 1
An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy
Thyroid Gland Carcinoma
M.D. Anderson Cancer Center42 enrolled1 locationNCT04589624
Recruiting
Phase 1
A Clinical Study of Cizutamig in Thyroid Eye Disease
Thyroid Eye Disease (TED)
Candid Therapeutics38 enrolled1 locationNCT07597200
Recruiting
Phase 1
Brodalumab in the Treatment of Immune-Related Adverse Events
Breast CancerLiver CancerEsophageal Cancer+15 more
Brian Henick, MD11 enrolled1 locationNCT06673329
Recruiting
Phase 1Phase 2
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
Breast CancerEsophageal CancerPancreatic Cancer+13 more
ModeX Therapeutics, An OPKO Health Company285 enrolled6 locationsNCT06239194
Recruiting
Phase 1
Lesion Dosimetry With Iodine-124 in Metastatic Thyroid Carcinoma
Thyroid CarcinomaMetastatic Thyroid Carcinoma
Memorial Sloan Kettering Cancer Center60 enrolled1 locationNCT03647358
Recruiting
Phase 1Phase 2
Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism
Hypoparathyroidism
Peking Union Medical College Hospital15 enrolled1 locationNCT07530705
Recruiting
Phase 1
Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer
Thyroid Gland Anaplastic CarcinomaBRAF NP_004324.2:p.V600EBRAF V600K Mutation Present
City of Hope Medical Center6 enrolled3 locationsNCT03975231
Recruiting
Phase 1
Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors
Breast CancerHead and Neck Squamous Cell CarcinomaMetastatic Malignant Solid Neoplasm+14 more
Anusha Kalbasi18 enrolled3 locationsNCT04119024
Recruiting
Phase 1Phase 2
Parathyroid Allotransplant for Treatment of Hypoparathyroidism
HypoparathyroidismHypoparathyroidism Post-surgicalHypoparathyroidism Postprocedural
Peter Stock3 enrolled1 locationNCT06961071
Recruiting
Phase 1Phase 2
Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor
Colorectal, CancerCervical CancerLung Cancer+4 more
Sichuan Enray Pharmaceutical Sciences Company54 enrolled9 locationsNCT07433283
Recruiting
Phase 1
177Lu-CTR-FAPI for the Treatment of Thyroid Cancer
Thyroid Cancer
SHAOYAN LIU12 enrolled2 locationsNCT07438847
Recruiting
Phase 1
A Study of GenSci098 in Subjects With Active Thyroid Eye Disease
SafetyTolerabilityGenSci098+1 more
Changchun GeneScience Pharmaceutical Co., Ltd.76 enrolled1 locationNCT06569758
Recruiting
Phase 1Phase 2
Clinical Application of Al18F-NOTA-FAPI-04 PET/CT or PET/MRI Imaging in Malignant Tumor,Cardiovascular or Immune Disease
Malignant TumorHyperthyroidism, AutoimmuneCardiovascular Abnormalities
Peking Union Medical College Hospital600 enrolled1 locationNCT07400224
Recruiting
Phase 1
SLV-154 Treatment of Metastatic Solid Tumors
Breast Cancer MetastaticOvarian CancerEndometrial Cancer+7 more
Solve Therapeutics70 enrolled9 locationsNCT06771219