Transgenderism Clinical Trials

11 recruiting

Frequently Asked Questions

Common questions about Transgenderism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Phase 4

Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version

Reproductive IssuesTransgenderism
University of California, San Diego80 enrolled1 locationNCT07092527
Recruiting

Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System

Arterial StiffnessAdiposityEating Behavior+3 more
University of Leipzig80 enrolled1 locationNCT04838249
Recruiting

Transgender Men, Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINIC

Transgenderism
Marianne Andersen200 enrolled1 locationNCT04254354
Recruiting
Not Applicable

Prospective Imaging Assessment of Perineo-pelvic Static's Evolution After Sexual Reassignment Surgery in MtF Transgender Patient, by Peno-scrotal Inversion Vaginoplasty Technique (TRANSPELV)

Transgenderism
University Hospital, Limoges50 enrolled1 locationNCT06093724
Recruiting

Puberty Suppression and Cardiometabolic Health

Insulin Sensitivity/ResistanceEndothelial DysfunctionVascular Stiffness+1 more
University of Colorado, Denver30 enrolled1 locationNCT04482374
Recruiting

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth

Gender DysphoriaInsulin SensitivityTransgenderism
University of Colorado, Denver90 enrolled1 locationNCT04596592
Recruiting

Feminizing Treatment in Transgender Women and Non-binary Persons

Transgenderism
Odense University Hospital100 enrolled1 locationNCT05169762
Recruiting

Sexual Functioning After Erection Prosthesis Placement in Post Phalloplasty Transgender Persons

Sexual DysfunctionErectile DysfunctionGender Dysphoria+2 more
University Hospital, Ghent150 enrolled1 locationNCT06639776
Recruiting

Erectile Aid Use in Post-phalloplasty and Post-metoidioplasty Transgender Patients

Sexual DysfunctionErectile DysfunctionGender Dysphoria+1 more
University Hospital, Ghent1,000 enrolled1 locationNCT06639763
Recruiting
Not Applicable

Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.

Sexual DysfunctionErectile DysfunctionGender Dysphoria+2 more
University Hospital, Ghent40 enrolled2 locationsNCT05883553
Recruiting
Not Applicable

Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty

SurgeryGender DysphoriaTransgenderism+1 more
University Ghent290 enrolled2 locationsNCT06439290