Phase 2 Triple Negative Breast Cancer(TNBC) Clinical Trials

18 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 118 of 18 trials

Recruiting
Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

Breast CancerBreast NeoplasmHER2-negative Breast Cancer+7 more
Fudan University716 enrolled1 locationNCT05582499
Recruiting
Phase 2

Neoadjuvant Study of HIFU With or Without PD-1 Inhibitors Followed by Abraxane Plus Carboplatin in Triple-Negative Breast Cancer.

Triple Negative Breast Cancer(TNBC)
The First Affiliated Hospital with Nanjing Medical University58 enrolled1 locationNCT07394387
Recruiting
Phase 2

Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer

Breast CancerNode-positive Breast CancerHER2-Negative Breast Carcinoma+1 more
UNC Lineberger Comprehensive Cancer Center32 enrolled1 locationNCT07276880
Recruiting
Phase 1Phase 2

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Head and Neck Squamous Cell Carcinoma (HNSCC)Non-small Cell Lung Cancer (NSCLC)Triple Negative Breast Cancer(TNBC)+3 more
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.230 enrolled13 locationsNCT05985655
Recruiting
Phase 2

PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease

Breast CancerTriple Negative Breast Cancer(TNBC)Residual Disease+1 more
UNC Lineberger Comprehensive Cancer Center78 enrolled1 locationNCT07069595
Recruiting
Phase 2

Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer

Breast CancerMetastatic Breast CancerHER2-negative Breast Cancer+2 more
Fudan University160 enrolled1 locationNCT06649331
Recruiting
Phase 2

Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer

Breast CancerTriple Negative Breast Cancer(TNBC)Early Stage Breast Cancer+2 more
Sun Yat-sen University192 enrolled5 locationsNCT06768931
Recruiting
Phase 1Phase 2

Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)

HER2-positive Breast CancerTriple Negative Breast Cancer(TNBC)Breast Cancer (Locally Advanced or Metastatic)
Beijing Biotech60 enrolled1 locationNCT07486089
Recruiting
Phase 2

QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Triple-Negative Breast Cancer

Triple Negative Breast Cancer(TNBC)
Affiliated Hospital of Nantong University30 enrolled1 locationNCT07342283
Recruiting
Phase 1Phase 2

A Study of MR001 in Patients With Locally Recurrent or Metastatic Advanced Triple-Negative Breast Cancer (TNBC)

Triple Negative Breast Cancer(TNBC)
Shenzhen Majory Biotechnology Co., Ltd.42 enrolled1 locationNCT07208149
Recruiting
Phase 1Phase 2

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

Solid TumorsER+ Breast CancerTriple Negative Breast Cancer(TNBC)+2 more
Jacobio Pharmaceuticals Co., Ltd.102 enrolled8 locationsNCT05490472
Recruiting
Phase 2

The Optimal Radioimmunotherapy Combinations for Advanced TNBC

Triple Negative Breast Cancer(TNBC)
Sun Yat-sen University60 enrolled1 locationNCT06735131
Recruiting
Phase 2

Efficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC)

Triple Negative Breast Cancer(TNBC)
Rhizen Pharmaceuticals SA40 enrolled9 locationsNCT06189209
Recruiting
Phase 1Phase 2

A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Pancreatic Ductal Adenocarcinoma (PDAC)Triple Negative Breast Cancer(TNBC)Colorectal Cancer (CRC)+6 more
ITM Oncologics GmbH270 enrolled10 locationsNCT05706129
Recruiting
Phase 2

PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition With or Without Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Treatment Resistant Residual Triple Negative Breast Cancer

Breast NeoplasmTriple Negative Breast Cancer(TNBC)HRD
Institute of Cancer Research, United Kingdom119 enrolled6 locationsNCT03740893
Recruiting
Phase 1Phase 2

Circadian Rhythm Impact on TNBC Response to Neoadjuvant Immunotherapy

Triple Negative Breast Cancer(TNBC)
Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.20 enrolled1 locationNCT06880029
Recruiting
Phase 2

BrAin Metastasis in tripLe Negateive Breast Cancer: IvoneScimab and Trop2 ADC

Triple Negative Breast Cancer(TNBC)Brain Metastases
Fudan University39 enrolled1 locationNCT06793332
Recruiting
Phase 2

All Trans Retinoic Acid Combined with Toripalimab+Chemotherapy for Locally Advanced Inoperable or Metastatic Triple Negative Breast Cancer:a Multi-center, Multi-cohort Phase II Trial

Triple Negative Breast Cancer(TNBC)
Fudan University129 enrolled2 locationsNCT06636981