Xerostomia Clinical Trials

10 recruiting

Xerostomia Trials at a Glance

15 actively recruiting trials for xerostomia are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Nanjing, Cairo, and Baltimore. Lead sponsors running xerostomia studies include Ain Shams University, Leiden University Medical Center, and Hopital Foch.

Browse xerostomia trials by phase

Treatments under study

About Xerostomia Clinical Trials

Looking for clinical trials for Xerostomia? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Xerostomia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Xerostomia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Phase 1Phase 2

Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1

Radiation-Induced Xerostomia and Hyposalivation
RiboX Therapeutics Ltd.42 enrolled4 locationsNCT06714253
Recruiting
Phase 1

Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia

Xerostomia
University of Wisconsin, Madison36 enrolled1 locationNCT06392711
Recruiting
Phase 2

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
MeiraGTx, LLC276 enrolled33 locationsNCT05926765
Recruiting
Not Applicable

Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study

Head and Neck CancerHead and Neck NeoplasmsXerostomia
Universidad de Granada60 enrolled1 locationNCT05106608
Recruiting

Screening of Biomarkers and Related Mechanisms for RIX

Xerostomia Due to Radiotherapy (Disorder)
Second Affiliated Hospital, School of Medicine, Zhejiang University126 enrolled4 locationsNCT07170358
Recruiting
Phase 1

d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC

Xerostomia
Stanford University40 enrolled1 locationNCT04392622
Recruiting
Phase 1Phase 2

A Randomized Controlled Trial of Spermidine for the Prevention of Radiation-Induced Xerostomia in Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma)

Radiation-induced Xerostomia
West China Hospital58 enrolled1 locationNCT07035626
Recruiting
Not Applicable

Acupressure on Xerostomia in Head and Neck Cancer Patients

Head and Neck CancerXerostomia
The University of Hong Kong126 enrolled1 locationNCT06465628
Recruiting
Not Applicable

Interest of Auriculotherapy in the Treatment of Xerostomia

Xerostomia
Hopital Foch68 enrolled4 locationsNCT04222478
Recruiting

Screening of Biomarkers and Related Mechanisms for RIX

Xerostomia Due to Radiotherapy (Disorder)
The First Affiliated Hospital with Nanjing Medical University200 enrolled3 locationsNCT06700863
Recruiting

An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer

NeoplasmsXerostomiaTaste, Altered
Our Lady's Hospice and Care Services120 enrolled1 locationNCT06287294
Recruiting
Not Applicable

The Efficacy of Hibiscus Sabdariffa in Xerostomia

Radiation-induced Xerostomia
Ain Shams University40 enrolled1 locationNCT06413550
Recruiting
Not Applicable

Management of Radiotherapy-related Xerostomia With Green Tea and Peppermint

Radiation-induced Xerostomia
Ain Shams University40 enrolled2 locationsNCT06414161
Recruiting
Not Applicable

Xerostomia-optimised IMRT Versus Standard IMRT in NPC

Nasopharyngeal Carcinoma ,Xerostomia,Radiotherapy
Zhongshan People's Hospital, Guangdong, China524 enrolled1 locationNCT06282497
Recruiting
Not Applicable

A Mouth Education Program for Dry Mouth

Dry MouthEnd of LifeFrailty+1 more
Leiden University Medical Center228 enrolled1 locationNCT05964959