Inclisiran Clinical Trials

13 recruitingDrug
Phase 36Not Applicable1Phase 41Phase 21

Showing 113 of 13 trials

Recruiting
Phase 3

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals9 enrolled19 locationsNCT06597006
Recruiting
Phase 3

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Atherosclerotic Cardiovascular Disease (ASCVD)
Novartis Pharmaceuticals340 enrolled95 locationsNCT06813911
Recruiting
Phase 2

A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia

Hypercholesterolaemia
Novartis Pharmaceuticals120 enrolled26 locationsNCT07610278
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes

Acute Coronary Syndrome
Novartis Pharmaceuticals300 enrolled63 locationsNCT07102628
Recruiting
Phase 4

Dual PCSK9 Inhibition With Inclisiran and Alirocumab in Secondary Prevention

Atherosclerotic Cardiovascular Disease (ASCVD)Hypercholesterolemia
University Medical Centre Ljubljana60 enrolled1 locationNCT07581808
Recruiting
Phase 3

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals195 enrolled52 locationsNCT05682378
Recruiting
Phase 3

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals60 enrolled66 locationsNCT06597019
Recruiting

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

Heterozygous Familial HypercholesterolemiaAtherosclerotic Vascular Disease
Novartis Pharmaceuticals200 enrolled20 locationsNCT06958315
Recruiting

Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Inclisiran in Italy

Hypercholesterolemia
Federico II University3,000 enrolled1 locationNCT06287177
Recruiting

Leqvio rPMS (Regulatory Post-Marketing Surveillance in Korea)

Primary Hypercholesterolemia or Mixed Dyslipidemia
Novartis Pharmaceuticals1,500 enrolled4 locationsNCT06770543
Recruiting

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals2,382 enrolled20 locationsNCT06858332
Recruiting
Phase 3

The Prevent Coronary Artery Disease Trial

Atherosclerotic Cardiovascular Disease
Icahn School of Medicine at Mount Sinai1,600 enrolled1 locationNCT06494501
Recruiting
Not Applicable

PET Imaging of Inflammation and Lipid Lowering Study

AtherosclerosisHypercholesterolemiaCarotid Artery Plaque+1 more
University of Cambridge63 enrolled1 locationNCT04073797