Stereotactic Radiosurgery Clinical Trials

20 recruitingRadiation
Phase 211Phase 15Phase 34Not Applicable3

Showing 120 of 20 trials

Recruiting
Not Applicable

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmMetastatic Malignant Neoplasm in the Spine
Ohio State University Comprehensive Cancer Center200 enrolled1 locationNCT05178472
Recruiting
Phase 1Phase 2

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

Lung CancerNSCLCBrain Metastases
Joshua Palmer56 enrolled3 locationsNCT05987644
Recruiting
Phase 3

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+7 more
NRG Oncology269 enrolled263 locationsNCT06500455
Recruiting
Phase 2

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

Ryan Gentzler, MD30 enrolled3 locationsNCT06248606
Recruiting
Phase 3

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Stage IV Lung Cancer AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Lung Small Cell Carcinoma+1 more
NRG Oncology200 enrolled227 locationsNCT04804644
Recruiting
Phase 2

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

Metastatic Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the Brain
Mayo Clinic90 enrolled7 locationsNCT05222620
Recruiting
Phase 2

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Lung CancerBrain Metastases, AdultBrain Metastases+1 more
Memorial Sloan Kettering Cancer Center62 enrolled7 locationsNCT05419076
Recruiting
Phase 2

Risk Adapted Spinal Cord/Cauda Constraint Relaxation for High-risk Patients With Metastatic Epidural Spinal Cord Compression Undergoing Spine Stereotactic Radiosurgery

Spinal CordMetastatic EpiduralSpine Stereotactic
M.D. Anderson Cancer Center60 enrolled1 locationNCT06204315
Recruiting
Phase 1

Hypophysectomy by Stereotactic Radiosurgery for Cancer-Related Pain

Hypophysectomy
M.D. Anderson Cancer Center40 enrolled1 locationNCT06287515
Recruiting
Phase 3

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the Brain
Mayo Clinic140 enrolled4 locationsNCT03750227
Recruiting
Phase 1Phase 2

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

Breast CancerBrain Metastases, Adult
Colette Shen41 enrolled7 locationsNCT04711824
Recruiting
Phase 2

Frameless Stereotactic Radiosurgery for Intact Brain Metastases

Brain Metastases
University of Chicago166 enrolled1 locationNCT02747303
Recruiting
Phase 2

EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active

Brain Metastases
M.D. Anderson Cancer Center316 enrolled1 locationNCT06649058
Recruiting
Phase 3

Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases

Metastatic Malignant Neoplasm in the BrainMalignant Neoplasm
M.D. Anderson Cancer Center180 enrolled1 locationNCT03741673
Recruiting
Not Applicable

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

Neoplasm MetastasisSpinal Cord Diseases
Henry Ford Health System60 enrolled1 locationNCT05023772
Recruiting
Not Applicable

Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

Metastatic Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the Brain
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University90 enrolled2 locationsNCT03184038
Recruiting
Phase 1

Stereotactic Radiosurgery Dose Escalation for Brain Metastases

Brain Metastases
University of Utah50 enrolled1 locationNCT02390518
Recruiting
Phase 2

Stereotactic Radiosurgery and Immunotherapy (Pembrolizumab) for the Treatment of Recurrent Meningioma

Grade I Meningioma, AdultGrade II Meningioma, AdultGrade III Meningioma, Adult+1 more
Nancy Ann Oberheim Bush, MD37 enrolled1 locationNCT04659811
Recruiting
Phase 1Phase 2

Neurocognitive Decline in Patients With Brain Metastases

Brain Metastases
University of Texas Southwestern Medical Center80 enrolled1 locationNCT03508752
Recruiting
Phase 2

Stereotactic Radiosurgery in the Treatment of Essential Tremor

Essential Tremor
Maria Sklodowska-Curie National Research Institute of Oncology42 enrolled1 locationNCT06821906