City of Hope Medical Center

Duarte, California, United States

140 recruiting

Showing 120 of 182 trials

Recruiting
Phase 1

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Intrahepatic CholangiocarcinomaGallbladder CarcinomaMetastatic Malignant Neoplasm in the Peritoneum+5 more
City of Hope Medical Center12 enrolled1 locationNCT05285358
Recruiting
Phase 1

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMyelodysplastic Syndrome
City of Hope Medical Center15 enrolled1 locationNCT06287944
Recruiting
Phase 1Phase 2

Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma

Recurrent Mycosis FungoidesRefractory Mycosis FungoidesSezary Syndrome+5 more
City of Hope Medical Center78 enrolled4 locationsNCT03011814
Recruiting
Phase 2

A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer

Prostate CancerProstate AdenocarcinomaLocalized Prostate Carcinoma
City of Hope Medical Center102 enrolled10 locationsNCT05751434
Recruiting
Phase 1

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

Hematopoietic and Lymphatic System NeoplasmAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+9 more
City of Hope Medical Center46 enrolled3 locationsNCT07020533
Recruiting
Phase 1

AOH1996 for the Treatment of Refractory Solid Tumors

Pancreatic CancerOvarian CancerNon-small Cell Lung Cancer+4 more
City of Hope Medical Center92 enrolled3 locationsNCT05227326
Recruiting
Phase 1Phase 2

Denosumab for Type 1 Diabetes

Type 1 Diabetes
City of Hope Medical Center45 enrolled3 locationsNCT06524960
Recruiting
Phase 1

A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
City of Hope Medical Center12 enrolled1 locationNCT06763341
Recruiting
Phase 3

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Ovarian Cancer
Incyte Corporation466 enrolled178 locationsNCT07214779
Recruiting
Phase 1

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Malignant Uterine NeoplasmPeritoneal CarcinomatosisClinical Stage IV Gastric Cancer AJCC v8+24 more
City of Hope Medical Center49 enrolled3 locationsNCT04329494
Recruiting
Phase 1

TMLI and Alemtuzumab for Treatment of Sickle Cell Disease

Sickle Cell Disease
City of Hope Medical Center20 enrolled1 locationNCT05384756
Recruiting
Phase 1

Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

Stage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8Locally Advanced Rectal Adenocarcinoma
City of Hope Medical Center36 enrolled1 locationNCT06834126
Recruiting
Phase 1Phase 2

Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

Mantle Cell LymphomaBlastoid Variant Mantle Cell LymphomaPleomorphic Variant Mantle Cell Lymphoma
City of Hope Medical Center50 enrolled3 locationsNCT05861050
Recruiting

Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

Hematopoietic and Lymphatic System NeoplasmMalignant Solid NeoplasmGraft-Versus-Host Disease
City of Hope Medical Center75 enrolled1 locationNCT07235501
Recruiting
Phase 1

Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer

Breast CarcinomaColorectal Carcinoma
City of Hope Medical Center24 enrolled1 locationNCT06130826
Recruiting

Pancreatic Cancer Detection Consortium

Pancreatic CancerPancreatic CarcinomaPancreatic Ductal Adenocarcinoma+10 more
City of Hope Medical Center2,000 enrolled11 locationsNCT06388967
Recruiting
Phase 1

Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant

Acute Myeloid LeukemiaMyelodysplastic Syndrome
City of Hope Medical Center43 enrolled1 locationNCT06498973
Recruiting
Phase 1

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8Metastatic Clear Cell Renal Cell Carcinoma+3 more
City of Hope Medical Center33 enrolled2 locationsNCT07128680
Recruiting
Not Applicable

Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy

Prostate Carcinoma
City of Hope Medical Center60 enrolled1 locationNCT07218718
Recruiting
Phase 1

Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia
City of Hope Medical Center26 enrolled1 locationNCT07133997