Clinical Trials in Morrisville, North Carolina
33 recruiting
Showing 1–20 of 33 trials
Recruiting
Phase 3
A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment
homocystinuria
Travere Therapeutics, Inc.70 enrolled52 locationsNCT06247085
Recruiting
Phase 1Phase 2
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
Chronic Obstructive Pulmonary DiseaseNon-cystic Fibrosis Bronchiectasis
Genentech, Inc.128 enrolled7 locationsNCT06603246
Recruiting
Phase 2
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
Primary Biliary CholangitisPBC
Mirum Pharmaceuticals, Inc.260 enrolled130 locationsNCT05050136
Recruiting
Phase 3
An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
Lennox Gastaut Syndrome
Epygenix260 enrolled20 locationsNCT05066217
Recruiting
Phase 3
A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma
Non-Hodgkin LymphomaBacterial InfectionsHypogammaglobulinemia+2 more
Grifols Therapeutics LLC386 enrolled62 locationsNCT05645107
Recruiting
Phase 1
Nalmefene Implant in Healthy Subjects
Opioid Abuse and Addiction
ReacX Pharmaceuticals, Inc.24 enrolled1 locationNCT07325279
Recruiting
Phase 3
Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)
Von Willebrand Disease (vWD)
Vega Therapeutics, Inc60 enrolled14 locationsNCT07115004
Recruiting
Phase 4
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
Percutaneous Coronary InterventionPeripheral Endovascular Intervention
Duke University6,000 enrolled78 locationsNCT06909565
Recruiting
Phase 3
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)
Idiopathic Hypersomnia
Harmony Biosciences Management, Inc.248 enrolled12 locationsNCT07500090
Recruiting
Phase 2Phase 3
A Phase 2/3 Study in Adult and Adolescent Participants With SCD
Sickle Cell Disease
Pfizer389 enrolled49 locationsNCT05431088
Recruiting
Phase 3
A Study of Pitolisant in Patients With Prader-Willi Syndrome
Prader-Willi Syndrome
Harmony Biosciences Management, Inc.134 enrolled54 locationsNCT06366464
Recruiting
Phase 3
A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy
Multifocal Motor Neuropathy (MMN)MMN
argenx115 enrolled109 locationsNCT06742190
Recruiting
Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
Chronic Granulomatous Disease (CGD)
Ensoma60 enrolled52 locationsNCT06605378
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled107 locationsNCT06481891
Recruiting
Phase 4
Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis
Kidney TransplantFocal Segmental GlomerulosclerosisProteinuria+1 more
Travere Therapeutics, Inc.20 enrolled9 locationsNCT07219121
Recruiting
Phase 2
A Phase 2 Study of CRD-4730 in CPVT
Catecholaminergic Polymorphic Ventricular Tachycardia
Cardurion Pharmaceuticals, Inc.12 enrolled9 locationsNCT06658899
Recruiting
Phase 3
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
Metastatic HER2-positive Breast Cancer
Jazz Pharmaceuticals550 enrolled166 locationsNCT06435429
Recruiting
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Rheumatoid ArthritisOsteoarthritis, KneePolyarthritis+6 more
Zimmer Biomet760 enrolled16 locationsNCT05787821
Recruiting
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis
Atopic DermatitisPregnancy Related
Incyte Corporation5,621 enrolled1 locationNCT06627335
Recruiting
Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population
Atopic DermatitisPregnancy Related
Incyte Corporation958 enrolled1 locationNCT06259669