HIIT Effects on Cardiometabolic Health
Detraining Effect of Short-term HIIT on Cardiometabolic Risk in Young Adults With Obesity
Syracuse University
60 participants
Sep 29, 2023
INTERVENTIONAL
Conditions
Summary
The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-rest ratios: 1) HIIT-A, 2) HIIT-B, 3) HIIT-C, and 4) control group. HIIT-A, HIIT-B, and HIIT-C groups will participate in six sessions of a running based HIIT program over a 2-week training period. Pre-clinical markers of cardiovascular disease, blood lipids and fasting glucose will be measured at the following three time points: baseline, post-intervention, and 2 weeks after the training cessation (i.e., measure for detraining effect). All measurements will be performed three days before the training program and three days after the intervention to avoid the effect of the last training session. Afterwards, the detraining test will be measured 2 weeks post intervention.
Eligibility
Inclusion Criteria1
- Young adults with obesity (Age 18 to 25 years old, BMI ≥ 30 kg/m2).
Exclusion Criteria7
- Syndromic obesity; 1) Any clinical symptoms including cognitive delay, 2) abnormalities in body structure(s), 3) organ-specific abnormalities (kidney, liver failure, excessive eating, and/or other signs of hypothalamic dysfunction such as fatigue, weakness and/or lack of interest in activities.
- Taking weight loss medication(s)
- Currently enrolled (or within previous 6 months) in a weight loss program;
- An underlying disease/medications (steroids, second generation psychotropic agents, hormonal contraception, statins, antihypertensive and antidiabetic medications) that could influence carbohydrate or lipid metabolism.
- Presence of cardiac pacemaker.
- Current or anticipated participation in another research that would interfere with any of the outcomes.
- Current or anticipated pregnancy.
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Interventions
Intervention groups include 3 arms with 3 different HIIT protocols to identify optimal exercise regimen for improving cardiometabolic health in young adults with obesity.
Locations(1)
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NCT05838950