Effects of Hemp-Derived Cannabinoids on Menopause Symptoms

This trial is studying whether hemp-derived cannabinoids (CBD and other non-THC compounds from hemp) can reduce menopause symptoms such as hot flashes, sleep problems, mood changes, and anxiety. Participants will take a standardized hemp extract for several weeks and report their symptoms via a smartphone app. **You may be eligible if...** - You were designated female at birth and are 40 to 60 years old - You are perimenopausal or menopausal - You have not used cannabis regularly in the past year (and are willing to abstain for 3 months) - You have a stable medication regimen (no changes in the past 3 months) - You own a smartphone and have access to Zoom on a stable internet connection **You may NOT be eligible if...** - You are currently taking antidepressants, anti-anxiety, or antipsychotic medications - You have a personal or family history of psychosis - You are pregnant or breastfeeding - You have hypotension (low blood pressure) - You are currently undergoing chemotherapy Talk to your doctor to see if this trial is right for you.