IL-6 and Hemogram-Derived Inflammatory Indices for Mortality Prediction in Postoperative ICU Patients
The Effects of IL-6 and Inflammation Scores on Mortality in Postoperative Patients Admitted to the Intensive Care Unit
Ezgi Günaydın
42 participants
Dec 15, 2025
OBSERVATIONAL
Conditions
Summary
This prospective observational cohort study aims to evaluate the predictive value of interleukin-6 (IL-6) levels and hemogram-derived inflammatory scores for morbidity and in-hospital mortality in postoperative patients admitted to the intensive care unit (ICU). IL-6 levels and inflammatory indices will be assessed at ICU admission and at 24 hours using data obtained from routine clinical care. Associations between these biomarkers and clinical outcomes, including mortality, morbidity, antibiotic use, and duration of mechanical ventilation, will be evaluated after adjustment for illness severity.
Eligibility
Inclusion Criteria4
- Age ≥ 18 years
- Postoperative patients admitted to the ICU
- Availability of complete clinical and laboratory data at ICU admission and at 24 hours
- Provision of informed consent by the patient or legally authorized representative
Exclusion Criteria3
- Age \< 18 years
- Thoracic surgery patients
- Cardiac surgery patients
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07460141