RecruitingNot ApplicableNCT07669168

Health Ahead Comparative Effectiveness Study

Health Ahead: Sequential Comparative-Effectiveness Studies Toward Automated, Universally Deployable Preventive Health Screening

Sponsor

William Brandenburg, MD

Enrollment

1,000,000 participants

Start Date

Jun 9, 2026

Study Type

INTERVENTIONAL

Conditions

Cardiovascular Diseases Metabolic Syndrome Cognitive Dysfunction Patient Participation Telemedicine Health Behavior Frailty Aging Health-related Quality of Life Rural Health Activities of Daily Living Health Equity Preventive Health Services Health Services Accessibility Medically Underserved Area

Summary

The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening system deployable in any environment, including the most isolated and resource-limited communities. Each change is isolated as a single variable against current practice, and every comparison is evaluated with a common set of engagement, behavior-change, experience, cost, and longitudinal outcome measures, so results accumulate on a consistent yardstick across the life of the platform. The first comparison evaluates AI-assisted versus human-only interpretation ("reads") of screening data. Subsequent pre-planned comparisons, added by protocol amendment, evaluate static versus interactive personalized report delivery; mobile community versus fixed laboratory screening; and a hybrid medical-droid-plus-human delivery model versus human-only screening.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Hybrid Medical Droid and Human Delivered Health Screenings, a behavioral approach called Interactive Personalized Health Report, and others for people with activities of daily living, aging, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALAI-Assisted Screening Interpretation (AI Reads)

An AI-generated read of the acquired screening battery is produced and presented to the physician of record as a clinical aid. All models used are third-party models, executed unmodified on Longevity Metrics clinical infrastructure. The physician reviews each read, records a structured judgment before sign-off, and then produces and signs the released interpretation, which may adopt, modify, or reject any read.

BEHAVIORALHuman-Only Screening Interpretation

All acquired screening data, images, tracings, and laboratory results are interpreted by the physician of record and qualified clinical staff under physician supervision, by standard practice and without AI decision support. This is the current standard of care and the active comparator.