Adrenal Insufficiency Clinical Trials

9 recruiting

Adrenal Insufficiency Trials at a Glance

11 actively recruiting trials for adrenal insufficiency are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Odense, Copenhagen, and Aarhus. Lead sponsors running adrenal insufficiency studies include Dr Morton Burt, Duke University, and Assistance Publique - Hôpitaux de Paris.

Browse adrenal insufficiency trials by phase

Treatments under study

About Adrenal Insufficiency Clinical Trials

Looking for clinical trials for Adrenal Insufficiency? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Adrenal Insufficiency trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Adrenal Insufficiency clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting

Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion

Primary AldosteronismAdrenal InsufficiencyAutonomous Cortisol Secretion
Qifu Li521 enrolled1 locationNCT06955286
Recruiting

Evaluation of Children With Endocrine and Metabolic-Related Conditions

Metabolic DiseaseAdrenal InsufficiencyBone Diseases, Metabolic+2 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)15,000 enrolled1 locationNCT02769975
Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Heart FailurePainInsomnia+22 more
Duke University5,000 enrolled51 locationsNCT04278404
Recruiting
Phase 4

Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency

Adrenal InsufficiencyGiant Cell ArteritisPolymyalgia Rheumatica
Marianne Christina Klose250 enrolled3 locationsNCT05435781
Recruiting
Not Applicable

Updated Diagnostic Cortisol Values for Adrenal Insufficiency

Adrenal Insufficiency
Montefiore Medical Center90 enrolled1 locationNCT05149638
Recruiting
Phase 4

Hydrocortisone and Placebo in Patients With Symptoms of Adrenal Insufficiency After Cessation of Glucocorticoid Treatment

Adrenal InsufficiencyGiant Cell Arteritis (GCA)Polymyalgia Rheumatica (PMR)
Marianne Andersen100 enrolled3 locationsNCT05193396
Recruiting

Establishment and Clinical Application of Reference Intervals of Salivary Cortisol

Cushing SyndromeAdrenal InsufficiencyHealthy Adult
Shanghai 6th People's Hospital220 enrolled1 locationNCT07168122
Recruiting

A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

Adrenal InsufficiencyHypercortisolismEndogenous Cushing Syndrome
University of Michigan12 enrolled1 locationNCT06430528
Recruiting

A Swiss Assessment of Hypothalamic-pituitary-adrenal Axis Suppression After Glucocorticoid Therapy for Leukemia and Lymphoblastic Lymphoma in Children

Adrenal InsufficiencyLeukemia, Lymphoblastic, Acute, PediatricLymphoma, Lymphoblastic
University Children's Hospital Basel40 enrolled2 locationsNCT06861530
Recruiting
Not Applicable

Genomic and Metabolomic Markers Reflecting the Complications of Hypercortisolism (CUSHINGOMICS)

Adult Glucocorticoid ExcessAdult Adrenal Insufficiency
Assistance Publique - Hôpitaux de Paris540 enrolled1 locationNCT04840693
Recruiting

Effect of steroids on blood sugar levels and risk of heart disease in pituitary patients

HypopituitarismSecondary adrenal insufficiency
Dr Morton Burt20 enrolled1 locationACTRN12612000234819