Phase 2 Advanced Colorectal Cancer Clinical Trials

10 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 110 of 10 trials

Recruiting
Phase 2

TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer

Colorectal Cancer MetastaticAdvanced Colorectal Cancer
Suzhou Teligene Ltd.80 enrolled1 locationNCT06589830
Recruiting
Phase 2

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

Advanced Colorectal Cancer
M.D. Anderson Cancer Center33 enrolled1 locationNCT06369259
Recruiting
Phase 2

Clinical Study on the First-line Treatment of Advanced Colorectal Cancer With Simultaneous Infusion of Levozolinate for Injection and 5-FU

Advanced Colorectal Cancer
Chinese PLA General Hospital583 enrolled1 locationNCT07391618
Recruiting
Phase 2

Irinotecan Liposome Plus Capecitabine and Enronsubemab Combined With Short-course Radiotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Advanced Colorectal Cancer
Tianjin Medical University Cancer Institute and Hospital30 enrolled1 locationNCT07281157
Recruiting
Phase 2

Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer

Metastatic Colorectal CancerAdvanced Colorectal Cancer
Riboscience, LLC.150 enrolled3 locationsNCT06824064
Recruiting
Phase 1Phase 2

First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer

Unresectable Metastatic Colorectal CancerUnresectable Locally Advanced Colorectal Cancer
Brenus Pharma90 enrolled9 locationsNCT06934538
Recruiting
Phase 2

Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer

Locally Advanced Colorectal Cancer
National University Hospital, Singapore20 enrolled1 locationNCT06846268
Recruiting
Phase 2

A Phase 2 Study Evaluating the Safety and Efficacy of JS207 With or Without JS015 in Combination With Chemotherapy in Patients With Colorectal Cancer

Advanced Colorectal Cancer
Shanghai Junshi Bioscience Co., Ltd.60 enrolled2 locationsNCT06885385
Recruiting
Phase 2

The Aim of This Study is to Assess the Efficacy and Safety of Chidamide, Regorafenib in Combination With Iparomlimab and Tuvonralimab for the Treatment of Advanced Colorectal Cancer in Third-line Therapy and Subsequent Lines.

Advanced Colorectal Cancer in the Third-line Treatment and BeyondpMMR/MSS Advanced Colorectal Cancer
Shanghai Changzheng Hospital60 enrolled1 locationNCT06930118
Recruiting
Phase 2

CapeOX Combined With Bevacizumab Plus Anti-PD1 Antibody as Neoadjuvant Therapy for Microsatellite Stable Locally Advanced Rectal Cancer

Locally Advanced Colorectal Cancer
Shanghai Changzheng Hospital30 enrolled1 locationNCT05585814