Phase 3 AMI Clinical Trials
49 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 49 trials
Recruiting
Phase 3
A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals60 enrolled35 locationsNCT07037771
Recruiting
Phase 2Phase 3
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC153 enrolled25 locationsNCT07058077
Recruiting
Phase 3
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals195 enrolled52 locationsNCT05682378
Recruiting
Phase 3
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis
Interstitial Lung DiseasesFamilial Pulmonary FibrosisInterstitial Lung Abnormalities
Boehringer Ingelheim80 enrolled56 locationsNCT07201922
Recruiting
Phase 2Phase 3
Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers
PharmacokineticsPharmacodynamicsInsulin Aspart
Amphastar Pharmaceuticals, Inc.60 enrolled1 locationNCT07560150
Recruiting
Phase 3
Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea
FHA (Functional Hypothalamic Amenorrhea)
Massachusetts General Hospital114 enrolled2 locationsNCT06533865
Recruiting
Phase 3
Nebulized Ketamine for the Treatment of Major Depressive Disorder
MidazolamDepressive SymptomSevere Depression+14 more
Theresa Jacob, PhD, MPH40 enrolled1 locationNCT06752759
Recruiting
Phase 3
IBI306 Monotherapy in Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
Innovent Biologics (Suzhou) Co. Ltd.198 enrolled1 locationNCT07473960
Recruiting
Phase 3
A Phase 3 Study of NTLA-2001 in ATTRv-PN
Nervous system diseasePeripheral nervous system diseaseAmyloidosis+17 more
Intellia Therapeutics60 enrolled14 locationsNCT06672237
Recruiting
Phase 3
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
Cardiovascular RiskAcute Myocardial Infarction (AMI)
Novo Nordisk A/S10,000 enrolled970 locationsNCT06118281
Recruiting
Phase 3
A Study to Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.760 enrolled2 locationsNCT07421297
Recruiting
Phase 3
Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction
Coronary Artery DiseaseAcute Myocardial Infarction (AMI)Coronary Atherosclerosis of Native Coronary Artery
ECRI bv332 enrolled1 locationNCT07276282
Recruiting
Phase 2Phase 3
Efficacy Testing of a Multi-Level Family Planning Intervention
Unintended pregnancyFamily Planning
Boston College1,464 enrolled1 locationNCT06923189
Recruiting
Phase 3
Effect of Adding a Low-Dose Epinephrine Bolus Prior to Infusion on Maternal Hemodynamic Stability During Cesarean Section
Hemodynamic (MAP) Stability
Cairo University100 enrolled1 locationNCT07480889
Recruiting
Phase 3
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled26 locationsNCT06950385
Recruiting
Phase 3
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals9 enrolled18 locationsNCT06597006
Recruiting
Phase 3
Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder
methamphetamine abuseMethamphetamine Dependence
National Institute on Drug Abuse (NIDA)360 enrolled11 locationsNCT06233799
Recruiting
Phase 2Phase 3
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
DementiaAlzheimers DiseaseAlzheimers Disease, Familial
Washington University School of Medicine280 enrolled35 locationsNCT05552157
Recruiting
Phase 2Phase 3
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
DementiaAlzheimers DiseaseAlzheimers Disease, Familial
Washington University School of Medicine280 enrolled35 locationsNCT06647498
Recruiting
Phase 3
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc.39 enrolled11 locationsNCT06760546