Phase 3 Analgesia Clinical Trials

20 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 20 trials

Recruiting
Phase 3

Efficacy of EXPAREL vs. Bupivacaine

Total Ankle ArthroplastyPostsurgical Analgesia
Emory University104 enrolled1 locationNCT07212114
Recruiting
Phase 3

Optimizing Pain Treatment in Children On Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaAnalgesics, Opioid+1 more
Weill Medical College of Cornell University644 enrolled15 locationsNCT06994442
Recruiting
Phase 3

Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

Prostate CancerOpioid Consumption, PostoperativeMultimodal Analgesia+2 more
Brigham and Women's Hospital300 enrolled2 locationsNCT07427043
Recruiting
Phase 2Phase 3

Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb Surgery

Post Operative AnalgesiaBradycardiaHypotension Drug-Induced
Sahiwal medical college sahiwal60 enrolled1 locationNCT07221682
Recruiting
Phase 3

Ropivacaine and Fentanyl for Labor Epidural Initiation

PregnancyLabor and DeliveryLabor Analgesia
University of California, San Francisco50 enrolled1 locationNCT07076368
Recruiting
Phase 2Phase 3

Comparative Analysis Of Dexmedetomidine And Dexamethasone As An Adjuvant To 0.5%Ropivacaine On Onset Of Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb Surgeries

HypotensionPost Operative AnalgesiaBradycardia+1 more
Sahiwal medical college sahiwal66 enrolled1 locationNCT07290595
Recruiting
Phase 3

Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery

Post Operative Analgesia
Al-Azhar University75 enrolled2 locationsNCT06665438
Recruiting
Phase 2Phase 3

Perioperative Analgesia Modes in Minimally Invasive Esophagectomy

Esophageal CancerPerioperative AnalgesiaNSAIDs+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences102 enrolled1 locationNCT05504265
Recruiting
Phase 3

Fentanyl or Esketamine for Traumatic PAIN (FORE-PAIN) Trial

AnalgesiaEsketamineFentanyl+2 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)608 enrolled1 locationNCT06051227
Recruiting
Phase 3

PROMPT: PROcedural sedation vs Methoxyflurane a Prospective cohorT Study.

Interventional Radiology procedural analgesia
South Western Sydney Local Health District Human Research Ethics Committee150 enrolled1 locationACTRN12623001127695
Completed
Phase 3

Lignocaine versus Opioids in Coronary Intervention: Assessing Antiplatelet Activity and Ticagrelor Levels (LOCAL) study

Analgesia
Alfred Health70 enrolled1 locationACTRN12619000648123
Not Yet Recruiting
Phase 3Phase 4

Pain relief and safety of the Erector Spinae Block in patients undergoing chest surgery

Erector Spinae BlockThoracic Surgery Analgesia
RBWH Anaesthetic Department50 enrolled2 locationsACTRN12618001495213
Terminated
Phase 3

dexamethasone and tramadol as additives to local anesthetics in ultrasound guided supraclavicular brachial plexus (SCBP) block and duration of analgesia.

analgesia after ultrasound guided nerve block
Tunisian Military Hospital60 enrolled1 locationACTRN12612000921886
Completed
Phase 3

Pharmacokinetics of 0.25% levobupivacaine with adrenaline following caudal epidural administration in children

Children undergoing elective sub-umbilical surgical procedures for which caudal epidural analgesia is indicated.
Royal Children's Hospital60 enrolled1 locationACTRN12609000845235
Completed
Phase 3

Pharmacokinetics of 0.25% levobupivacaine with adrenaline and clonidine following caudal epidural administration in children

Children undergoing elective sub-umbilical surgical procedures for which caudal epidural analgesia is indicated.
Royal Children's Hospital60 enrolled1 locationACTRN12609000668202
Not Yet Recruiting
Phase 3

Pharmacokinetics of 0.25% levobupivacaine with clonidine following caudal epidural administration in children

Children undergoing elective sub-umbilical surgical procedures for which caudal epidural analgesia is indicated.
Royal Children's Hospital50 enrolled1 locationACTRN12609000126213
Completed
Phase 2Phase 3

Pilot Trial of Transversus Abdominis Plane Ropivacaine Infusions following Abdominal Surgery

Post-operative analgesia in patients undergoing abdominal surgeryAnalgesia in patients undergoing abdominal surgery
Western Health20 enrolled1 locationACTRN12608000291381
Completed
Phase 3

Maxi-Analgesic Junior Study

Children requiring analgesia post tonsillectomy
Hartley Atkinson, Managing Director, AFT Pharmaceuticals, Ltd150 enrolled2 locationsACTRN12607000005459
Completed
Phase 3

The effect of parecoxib on post craniotomy analgesia.

Postoperative analgesia for craniotomy surgery.
Department of Anaesthesia, St Vincent's Hospital Melbourne82 enrolled1 locationACTRN12605000600640
Completed
Phase 3Phase 4

A prospective randomised study comparing two techniques for establishing Continuous Femoral Nerve Blockade for postoperative analgesia following Total Knee Joint Replacement

Postoperative analgesia for Total Knee Joint Replacement
Department of Anaesthesia, St Vincent's Hospital Melbourne78 enrolled1 locationACTRN12605000417684