Bone Disease Clinical Trials

1 recruitingLast updated: May 4, 2026

Bone Disease Trials at a Glance

22 actively recruiting trials for bone disease are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Bethesda, Milan, and London. Lead sponsors running bone disease studies include National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Case Comprehensive Cancer Center, and Boston Children's Hospital.

Browse bone disease trials by phase

Treatments under study

About Bone Disease Clinical Trials

Looking for clinical trials for Bone Disease? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Bone Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Bone Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Not Applicable

"Pseudo-scanner" MRI Sequences for the Detection of Bone Lesions in Multiple Myeloma

Multiple Myeloma Bone Disease
Cliniques universitaires Saint-Luc- Université Catholique de Louvain45 enrolled1 locationNCT06988020
Recruiting

Evaluation of Children With Endocrine and Metabolic-Related Conditions

Metabolic DiseaseAdrenal InsufficiencyBone Diseases, Metabolic+2 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)15,000 enrolled1 locationNCT02769975
Recruiting

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

HypertensionCardiovascular DiseaseAdrenal Gland Neoplasm+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,150 enrolled1 locationNCT03374215
Recruiting

Lymphatic Anomalies Registry for the Assessment of Outcome Data

Lymphatic MalformationCLOVES SyndromeKaposiform Lymphangiomatosis+5 more
Boston Children's Hospital1,000 enrolled1 locationNCT02399527
Recruiting
Not Applicable

Musculoskeletal Cancers Remote Monitoring and Care

OsteosarcomaMetastatic Bone Disease
Case Comprehensive Cancer Center60 enrolled1 locationNCT07129226
Recruiting

Natural History Study of Parathyroid Disorders

Primary HyperparathyroidismParathyroid CancerPseudohypoparathyroidism+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)3,000 enrolled1 locationNCT04969926
Recruiting

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Musculoskeletal DiseasesOsteoarthritisJoint Diseases+3 more
Xiaojuan Li88 enrolled1 locationNCT04536103
Recruiting
Not Applicable

Glucose-dependent INsulinotropic Polypeptide: Effect on Bone Remodelling and Cell Activity (GINEBRA)

Diabetes Mellitus, Type 2Obesity and Obesity-related Medical ConditionsBone Disease, Metabolic
Esbjerg Hospital - University Hospital of Southern Denmark12 enrolled1 locationNCT06790225
Recruiting
Not Applicable

Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial

Metastatic Bone Disease
Michelle Ghert, MD334 enrolled6 locationsNCT06863129
Recruiting

Clinical Validation of BoneMRI in the Spine

ImageBone Diseases
MRIguidance B.V.450 enrolled10 locationsNCT06745791
Recruiting

Metabolic Profile of Bone in Professional Athletes

Physical ActivityBone Disease, Metabolic
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio200 enrolled1 locationNCT03386981
Recruiting
Early Phase 1

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

Prostate CancerObesityMetabolic Syndrome+4 more
Western University30 enrolled1 locationNCT05802121
Recruiting
Not Applicable

Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

Bone Disease, Metabolic
San Diego State University200 enrolled1 locationNCT06184646
Recruiting

RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study

Breast CancerBreast Cancer MetastaticBreast Carcinoma+9 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano500 enrolled1 locationNCT07030569
Recruiting

Fosfomycin I.v. for Treatment of Severely Infected Patients

OsteomyelitisEncephalitisSepsis+13 more
Infectopharm Arzneimittel GmbH1,000 enrolled50 locationsNCT02979951
Recruiting

Gene Expression Profiles in Spinal Tuberculosis.

Musculoskeletal DiseasesTuberculosisInfections+8 more
University of Cape Town100 enrolled1 locationNCT05610098
Recruiting

The Impact of Glomerular Disorders on Bone Quality and Strength

Bone FractureBone Diseases, MetabolicGlomerular Disease
Columbia University270 enrolled2 locationsNCT04528446
Recruiting

The Bone Metabolism Characteristics of Premature Ovarian Insufficiency

Premature Ovarian InsufficiencyBone Diseases, Metabolic
Shi Yun60 enrolled1 locationNCT06339489
Recruiting
Phase 4

Treatment of Adynamic Bone Disorder With Parathyroid Hormone in Chronic Kidney Disease

Chronic Kidney DiseasesCardiac DiseaseChronic Kidney Disease-Mineral and Bone Disorder+1 more
Ditte Hansen48 enrolled4 locationsNCT04522622
Recruiting

Exosome microRNAs as Potential Biomarkers of Metabolic Bone Disease of Prematurity

ExosomesBone Diseases, MetabolicNewborn
Hunan Children's Hospital200 enrolled1 locationNCT06368154