Brain Clinical Trials in Boston, Massachusetts
61 recruitingBoston, Massachusetts
Showing 1–20 of 61 trials
Recruiting
Phase 1Phase 2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Colorectal, CancerColorectal CarcinomaNon-small Cell Lung Cancer+29 more
Institut de Recherches Internationales Servier554 enrolled27 locationsNCT05786924
Recruiting
Phase 2
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
Breast CancerColorectal, CancerLung Cancer+13 more
Brigham and Women's Hospital134 enrolled2 locationsNCT04899908
Recruiting
Phase 1
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
MelanomaNon-small Cell Lung CancerThyroid Cancer+10 more
Pfizer124 enrolled82 locationsNCT05538130
Recruiting
Phase 1Phase 2
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Phase 1
A Phase 1/1b Study of IAM1363 in HER2 Cancers
HER2-positive Breast CancerHER2 + Breast CancerHER2 Mutation-Related Tumors+10 more
Iambic Therapeutics, Inc383 enrolled53 locationsNCT06253871
Recruiting
Phase 3
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
Stage IV Lung Cancer AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Lung Small Cell Carcinoma+1 more
NRG Oncology200 enrolled227 locationsNCT04804644
Recruiting
Phase 2
NTS-WBRT in Brain Metastases
Brain Metastases
Massachusetts General Hospital41 enrolled1 locationNCT05013892
Recruiting
Phase 1Phase 2
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
Lung CancerNon-small Cell Lung CancerSolid Tumor+4 more
Tango Therapeutics, Inc.191 enrolled15 locationsNCT06810544
Recruiting
Phase 3
A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma
Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled95 locationsNCT06388733
Recruiting
Phase 2
Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction
Brain Metastases, AdultBrain Tumor - MetastaticBrain Metastases From Non-small Cell Lung Cancer (NSCLC)+1 more
Ayal A. Aizer, MD60 enrolled1 locationNCT07132190
Recruiting
Phase 2
Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases
Brain Metastases, AdultBrain Metastases From Non-small Cell Lung Cancer (NSCLC)Brain Metastases From Extra-cranial Solid Tumors+2 more
Ayal A. Aizer, MD150 enrolled1 locationNCT07130786
Recruiting
Not Applicable
Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases
Brain Tumor
Brigham and Women's Hospital101 enrolled2 locationsNCT04033497
Recruiting
Phase 2
Palbociclib and Pembrolizumab In Central Nervous System Metastases
Metastatic Malignant Neoplasm to BrainRecurrent Brain MetastasesProgressive Brain Metastases
Massachusetts General Hospital45 enrolled2 locationsNCT02896335
Recruiting
Not Applicable
Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
Breast CancerChemo-brainImpaired Cognition
Massachusetts General Hospital200 enrolled2 locationsNCT02290834
Recruiting
Not Applicable
High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study
Pediatric Brain Tumor
Dana-Farber Cancer Institute30 enrolled1 locationNCT05740839
Recruiting
Not Applicable
Stereotactic Magnetic Resonance Guided Radiation Therapy
Prostate CancerLung CancerSpine Metastases+10 more
Dana-Farber Cancer Institute397 enrolled2 locationsNCT04115254
Recruiting
Not Applicable
ASCENT Intervention for Brain Tumor Patients
Distress, EmotionalGliomaMalignant Brain Tumor+1 more
Massachusetts General Hospital100 enrolled1 locationNCT06099743
Recruiting
Phase 2
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Pancreatic CancerGastric CancerLung Cancer+15 more
Apollomics Inc.497 enrolled35 locationsNCT03175224
Recruiting
The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)
GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+5 more
Jasper Gerritsen464 enrolled8 locationsNCT06283927
Recruiting
The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+2 more
Jasper Gerritsen564 enrolled8 locationsNCT06146725