Phase 4 Cardiac Clinical Trials
51 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 51 trials
Recruiting
Phase 4
LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery
myocardial injury after non-cardiac surgeryAutonomic DysfunctionCardiovascular (CV) Risk+3 more
Insel Gruppe AG, University Hospital Bern114 enrolled1 locationNCT07168421
Recruiting
Phase 4
Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIAL
Rheumatoid ArthritisMajor Adverse Cardiac Events
Shaikh Zayed Hospital, Lahore120 enrolled1 locationNCT07554820
Recruiting
Phase 4
The Leadless AV Versus DDD Pacing Study
Cardiovascular DiseasesArrhythmias, CardiacHeart Diseases+1 more
Insel Gruppe AG, University Hospital Bern100 enrolled1 locationNCT05498376
Recruiting
Phase 4
The STOP-MED CTRCD Trial
Heart FailureCancerCardiotoxicity+2 more
Dinesh Thavendiranathan335 enrolled14 locationsNCT06183437
Recruiting
Phase 4
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Postoperative PainPain After SurgeryCardiac Surgery Patient
Istanbul University - Cerrahpasa60 enrolled1 locationNCT07472959
Recruiting
Phase 4
The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery
Acute Kidney Injury (AKI)AnesthesiaMyocardial Injury After Noncardiac Surgery (MINS)+4 more
University of California, San Francisco18,000 enrolled8 locationsNCT06802224
Recruiting
Phase 4
Intrapleural Ropivacaine Infusion in Cardiac Surgery
Coronary Artery DiseaseCardiac SurgeryValvular Diseases
Saint Petersburg State University, Russia116 enrolled2 locationsNCT07116343
Recruiting
Phase 4
MEdical Treatment in Idiopathic Ventricular Fibrillation Patients
Cardiac Arrest, Out-Of-HospitalIdiopathic Ventricular Fibrillation
Bo Gregers Winkel218 enrolled2 locationsNCT07405229
Recruiting
Phase 4
Colchicine's Effect on Inflammatory Markers
ColchicinePost-operative Atrial FibrillationInflammation in Cardiac Surgery+2 more
Ayesha Ather24 enrolled1 locationNCT07287345
Recruiting
Phase 4
Oral Methadone in Cardiac Surgery
Pain, PostoperativeAnesthesiaCardiac Surgery
Mayo Clinic100 enrolled1 locationNCT07221617
Recruiting
Phase 4
Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc.200 enrolled16 locationsNCT07306949
Recruiting
Phase 4
Landiolol in Mitral Valve Surgery
Cardiac FailureLow Cardiac Output Syndrome
Università Vita-Salute San Raffaele1,500 enrolled13 locationsNCT06793670
Recruiting
Phase 4
ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)
Vasodilatory Hypotension During or After Cardiac Surgery
University of Maryland St. Joseph Medical Center100 enrolled1 locationNCT06487585
Recruiting
Phase 4
Epinephrine Dose: Optimal Versus Standard Evaluation Trial
Ventricular FibrillationSudden Cardiac ArrestCardiac Arrest, Out-Of-Hospital+1 more
Unity Health Toronto3,790 enrolled8 locationsNCT03826524
Recruiting
Phase 4
Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest
Cardiopulmonary ResuscitationCardiac ArrestRehabilitation+4 more
Rigshospitalet, Denmark214 enrolled1 locationNCT05173740
Recruiting
Phase 4
Efficacy and Safety Trials of Yangxinshi Tablets in the Treatment of Patients With Coronary Heart Disease Complicated by Cardiac Dysfunction
Cardiac dysfunctionCoronary Heart Disease
SPH Qingdao Growful Pharmacetical Co.,Ltd2,708 enrolled96 locationsNCT07110415
Recruiting
Phase 4
Ultrasound Therapy In Cardiac Amyloidosis
Amyloidosis Cardiac
Brigham and Women's Hospital70 enrolled1 locationNCT04667494
Recruiting
Phase 4
Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery
Cardiac Surgical Procedures
SHI Jia820 enrolled2 locationsNCT04244981
Recruiting
Phase 4
Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
CardiomyopathySudden Cardiac DeathHeart Failure With Reduced Ejection Fraction (HFrEF)+3 more
University of Rochester2,000 enrolled13 locationsNCT06964464
Recruiting
Phase 4
Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation
Transthyretin Cardiac Amyloidosis
University of Texas Southwestern Medical Center25 enrolled4 locationsNCT05489523