Phase 2 Cardiovascular Disease Clinical Trials
24 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 24 trials
Recruiting
Phase 2Phase 3
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
Atherosclerotic Cardiovascular Disease
CSL Behring2,310 enrolled542 locationsNCT05485961
Recruiting
Phase 2
Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis
ASCVDAtherosclerosis Cardiovascular DiseaseASCVD Management
Atom Therapeutics Co., Ltd200 enrolled33 locationsNCT07303777
Recruiting
Phase 2
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Cardiovascular DiseasesFibrosisLung Diseases+3 more
Pulmovant, Inc.20 enrolled1 locationNCT07333183
Recruiting
Phase 2
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)
Heart FailureCardiovascular DiseasesCKD
University Medical Center Groningen100 enrolled2 locationsNCT07304817
Recruiting
Phase 2
Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults
Cardiovascular Disease
National Heart, Lung, and Blood Institute (NHLBI)110 enrolled1 locationNCT03372733
Recruiting
Phase 2
The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD
Cardiovascular DiseaseSystemic Lupus ErythematosusPremature Atherosclerosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)45 enrolled1 locationNCT05440422
Recruiting
Phase 2Phase 3
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
ObesityCardiovascular DiseasesHypertension+3 more
University of Alabama at Birmingham160 enrolled1 locationNCT04971720
Recruiting
Phase 2
Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans
Cardiovascular Diseases
VA Office of Research and Development150 enrolled2 locationsNCT05423158
Recruiting
Phase 1Phase 2
TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVD
Endothelial DysfunctionAtherosclerotic Cardiovascular Diseases
Hudson Biotech80 enrolled1 locationNCT07487363
Recruiting
Phase 1Phase 2
Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases
TumorCardiovascular DiseasesPulmonary Fibrosis+3 more
Peking Union Medical College Hospital30 enrolled1 locationNCT07464132
Recruiting
Phase 2
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
Cardiovascular DiseasesAtherosclerosisLipid Disorder+1 more
Wake Forest University Health Sciences130 enrolled1 locationNCT06488105
Recruiting
Phase 2
Omega-3D: Omega-3 for Diet-Driven Health Disparities
Cardiovascular DiseasesOmega 3 Fatty AcidsHeart Health Markers
University of Arizona200 enrolled2 locationsNCT07078344
Recruiting
Phase 2
Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)
Cardiovascular DiseasesHIV InfectionsAtherosclerosis+1 more
Priscilla Hsue, MD121 enrolled3 locationsNCT05488431
Recruiting
Phase 2
[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease
Atherosclerosis Cardiovascular DiseaseStroke (CVA) or TIACarotid Artery Plaque+1 more
Universitaire Ziekenhuizen KU Leuven24 enrolled1 locationNCT07104487
Recruiting
Phase 2
NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals
Diabetes MellitusInsulin Sensitivity/ResistanceCardiovascular Diseases+4 more
University of Alabama at Birmingham200 enrolled1 locationNCT04055428
Recruiting
Phase 2
Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT
Cardiovascular DiseasesHIV InfectionsDysbiosis+2 more
Vanderbilt University Medical Center250 enrolled1 locationNCT05288790
Recruiting
Phase 1Phase 2
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
Cardiovascular DiseasesHypertension
University of Kansas Medical Center23 enrolled1 locationNCT04715022
Recruiting
Phase 1Phase 2
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 2
Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body
Heart FailureCardiometabolic SyndromeCardiovascular Diseases+2 more
National Heart Centre Singapore200 enrolled1 locationNCT06645691
Recruiting
Phase 2
Lumasiran in Hyperoxalaemic Patients on Haemodialysis
Cardiovascular DiseaseCardiovascular Risk FactorChronic Kidney Disease Requiring Chronic Dialysis+2 more
Charite University, Berlin, Germany50 enrolled1 locationNCT06225544