Phase 1 Cardiovascular Disease Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers
Cardiovascular Disease
National Heart, Lung, and Blood Institute (NHLBI)64 enrolled1 locationNCT04216342
Recruiting
Phase 1Phase 2
TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVD
Endothelial DysfunctionAtherosclerotic Cardiovascular Diseases
Hudson Biotech80 enrolled1 locationNCT07487363
Recruiting
Phase 1Phase 2
Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases
TumorCardiovascular DiseasesPulmonary Fibrosis+3 more
Peking Union Medical College Hospital30 enrolled1 locationNCT07464132
Recruiting
Phase 1
Fish Oil, Metformin and Heart Health in PCOS
Cardiovascular DiseasePCOSAtherosclerotic Plaque+2 more
University of Alberta146 enrolled3 locationsNCT06424860
Recruiting
Phase 1
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Cardiovascular DiseasesEndothelial DysfunctionType 1 Diabetes+2 more
Kalie Tommerdahl60 enrolled2 locationsNCT05065372
Recruiting
Phase 1Phase 2
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
Cardiovascular DiseasesHypertension
University of Kansas Medical Center23 enrolled1 locationNCT04715022
Recruiting
Phase 1Phase 2
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 1
A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study
NeoplasmsMultiple MyelomaCardiovascular Diseases+11 more
OriCell Therapeutics Co., Ltd.81 enrolled1 locationNCT06271252
Recruiting
Phase 1Phase 2
A Study to Evaluate Mesenchymal Stem Cell Product StromaForte's Effect on Cardiovascular Events
Cardiovascular Diseases
Cellcolabs Clinical LTD.100 enrolled1 locationNCT06087848
Not Yet Recruiting
Phase 1
A Safety and Tolerability Study Evaluating CTX320 in Subjects With Elevated Lipoprotein(a) and a History of Atherosclerotic Cardiovascular Disease or Calcific Aortic Valve Stenosis.
Elevated Lipoprotein(a)Atherosclerotic Cardiovascular DiseaseCalcific Aortic Valve Stenosis
CRISPR Therapeutics AG24 enrolled1 locationACTRN12623001095651
Recruiting
Phase 1
A pilot trial assessing the effect of fish oil on leptin and adiponectin levels in overweight/obese individuals.
ObesityCardiovascular Disease
Centre for Integrative Clinical and Molecular Medicine, University of Queensland48 enrolled1 locationACTRN12610000983000