Phase 4 Cardiovascular Clinical Trials

43 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 43 trials

Recruiting
Phase 4

Statins to Prevent Cancer Associated Blood Clots

CancerVenous ThromboembolismCardiovascular Events
Brigham and Women's Hospital4,000 enrolled2 locationsNCT07303816
Recruiting
Phase 4

Treatment With Aspirin After Preeclampsia: TAP Trial

Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Cardiovascular DiseasesDementiaCognitive Impairment, Mild
Duke University20,000 enrolled103 locationsNCT04262206
Recruiting
Phase 4

Dual PCSK9 Inhibition With Inclisiran and Alirocumab in Secondary Prevention

Atherosclerotic Cardiovascular Disease (ASCVD)Hypercholesterolemia
University Medical Centre Ljubljana60 enrolled1 locationNCT07581808
Recruiting
Phase 4

Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism

Cardiovascular DiseasesVenous ThromboembolismPulmonary Embolism+6 more
Drahomir Aujesky276 enrolled40 locationsNCT04263038
Recruiting
Phase 4

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

myocardial injury after non-cardiac surgeryAutonomic DysfunctionCardiovascular (CV) Risk+3 more
Insel Gruppe AG, University Hospital Bern114 enrolled1 locationNCT07168421
Recruiting
Phase 4

Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia

DementiaCardiovascular Disease
Tor Biering-Sørensen162,000 enrolled2 locationsNCT07485283
Recruiting
Phase 4

Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia

Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals326 enrolled1 locationNCT07034690
Recruiting
Phase 4

Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE

Cardiovascular DiseasesInflammatory ResponseAcute Myocardial Infarction
Region Örebro County90 enrolled3 locationsNCT06336317
Recruiting
Phase 4

The Leadless AV Versus DDD Pacing Study

Cardiovascular DiseasesArrhythmias, CardiacHeart Diseases+1 more
Insel Gruppe AG, University Hospital Bern100 enrolled1 locationNCT05498376
Recruiting
Phase 4

Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes

CardiovascularRed Blood Cell TransfusionsSex Differences+3 more
Michelle Zeller11,082 enrolled8 locationsNCT06840756
Recruiting
Phase 4

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

Cardiovascular ComplicationPre-EclampsiaGestational Hypertension+2 more
University of Michigan200 enrolled1 locationNCT06785116
Recruiting
Phase 4

ASpirin Use and stAtin Strategy for Primary Prevention in Severe Coronary Calcium Score on Computed Tomography

Cardiovascular Diseases
Jung-min Ahn5,000 enrolled1 locationNCT06676280
Recruiting
Phase 4

Randomized Trial of SGLT2i in Heart Transplant Recipients

Heart TransplantCardiovascular DiseaseKidney Disease
VA Office of Research and Development200 enrolled6 locationsNCT06625073
Recruiting
Phase 4

Iron Infusion in Patients Undergoing Transcatheter Aortic Valve Implantation

Cardiovascular DiseasesIron-deficiencyAortic Valve Stenosis+1 more
Erasmus Medical Center402 enrolled1 locationNCT07370688
Recruiting
Phase 4

Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >70 Years: the SCOPE-70 RCT Study

Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease
Yonsei University724 enrolled1 locationNCT03770312
Recruiting
Phase 4

Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

Cardiovascular Disease
University of North Carolina, Chapel Hill120 enrolled1 locationNCT06263452
Recruiting
Phase 4

Extended-Release Tacrolimus Following Liver Transplantation

Cardiovascular DiseasesMetabolic SyndromeLiver Transplant; Complications+2 more
University of Alberta94 enrolled1 locationNCT05242315
Recruiting
Phase 4

Secondhand Tobacco Smoke and Cardiovascular Disease

Cardiovascular DiseasesHypertension
University of California, San Francisco100 enrolled1 locationNCT04715568
Recruiting
Phase 4

Effect of Treatment With Finerenone on Cardio-Renal Target Organ Damage in Patients With Type 2 Diabetes.

Cardiovascular DiseasesType 2 Diabetes Mellitus (T2DM)Chronic Kidney Disease Due to Type 2 Diabetes Mellitus
University of Aarhus80 enrolled1 locationNCT07026539