Chronic Low-back Pain Clinical Trials

39 recruiting

Chronic Low-back Pain Trials at a Glance

39 actively recruiting trials for chronic low-back pain are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Kansas City, New Orleans, and Brussels. Lead sponsors running chronic low-back pain studies include Boston Scientific Corporation, Johns Hopkins University, and University of California, Los Angeles.

Browse chronic low-back pain trials by phase

Treatments under study

About Chronic Low-back Pain Clinical Trials

Looking for clinical trials for Chronic Low-back Pain? There are currently 39 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic Low-back Pain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic Low-back Pain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 39 trials

Recruiting

Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

Chronic Low-back PainVertebrogenic Pain Syndrome
Boston Scientific Corporation1,500 enrolled16 locationsNCT06827262
Recruiting
Not Applicable

High Frequency RF Current Effects on Muscle Pain and Function

Hamstring InjuryChronic Low-back PainPhysical Therapy+3 more
Aristotle University Of Thessaloniki200 enrolled2 locationsNCT05345015
Recruiting
Not Applicable

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

Chronic Low-back PainChronic PainLow Back Pain+1 more
Boston Scientific Corporation70 enrolled7 locationsNCT07190807
Recruiting
Not Applicable

Improving Health for Patients With Chronic LBP in Rural Communities Through Telerehabilitation

Chronic Low-back Pain
Johns Hopkins University434 enrolled2 locationsNCT06471920
Recruiting
Not Applicable

Clinician Satisfaction With the VERABAND™

Chronic Low-back Pain
University of Michigan360 enrolled3 locationsNCT06080464
Recruiting
Not Applicable

The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial

Chronic Low-back Pain
Oslo University Hospital202 enrolled5 locationsNCT06169488
Recruiting
Phase 2

Modulation Effect of tACS on Chronic Low Back Pain

Chronic Low-back Pain
Massachusetts General Hospital80 enrolled1 locationNCT06568198
Recruiting
Not Applicable

Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain

Chronic Low-back PainLow Back Pain
Edward Via Virginia College of Osteopathic Medicine200 enrolled1 locationNCT06818175
Recruiting
Not Applicable

Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

Chronic Low-back Pain
University of California, San Francisco50 enrolled1 locationNCT05265000
Recruiting
Not Applicable

"Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2)

Chronic Low-back PainDegenerative Disc Disease
Spinal Stabilization Technologies72 enrolled10 locationsNCT05508360
Recruiting
Not Applicable

AuriculoTherapy NeuroImaging

Chronic Low-back PainLumbar Discogenic PainLow Back Pain+7 more
Keith M Vogt60 enrolled1 locationNCT06825390
Recruiting
Phase 1Phase 2

Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain

Chronic Low-back PainDegenerative Disc Disease
Creative Medical Technology Holdings Inc45 enrolled1 locationNCT06053242
Recruiting
Not Applicable

Detection of EEG-Based Biomarkers of Chronic Low Back Pain

HealthyChronic Low-back Pain
Stanford University130 enrolled1 locationNCT06025201
Recruiting
Not Applicable

Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.

Chronic Low-back Pain
University of Kansas Medical Center50 enrolled1 locationNCT04730700
Recruiting
Phase 1Phase 2

Integrative Breathwork Intervention for Chronic Pain

Chronic Low-back Pain
University of Florida30 enrolled1 locationNCT06546956
Recruiting
Phase 1

Psilocybin in Chronic Low Back Pain and Depression

DepressionChronic Low-back Pain
Johns Hopkins University40 enrolled1 locationNCT06355414
Recruiting

Brain Imaging Biomarkers for Response to Spinal Cord Stimulation in Patients With Chronic Low Back Pain

Chronic Low-back Pain
University of California, Los Angeles42 enrolled1 locationNCT04658628
Recruiting

Motivations, Obstacles and Opportunities for Using a Health Application to Encourage Physical Activity in People With Chronic Low Back Pain

Chronic Low-back Pain
University Hospital, Clermont-Ferrand25 enrolled1 locationNCT06517342
Recruiting
Not Applicable

Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-center RCT

Chronic Low-back PainOverweight or Obesity
Vrije Universiteit Brussel252 enrolled2 locationsNCT05811624
Recruiting

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Failed Back Surgery SyndromePost Operative PainChronic Low-back Pain+12 more
Brown University800 enrolled1 locationNCT05754190