Phase 1 Chronic Pain Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1
Managing Chronic Tendon Pain by Metformin
Chronic PainAchilles tendinopathyTendinopathy
James Wang40 enrolled1 locationNCT06100822
Recruiting
Phase 1
STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis
Pancreatic SurgeryChronic PainChronic Pancreatitis+7 more
Indiana University24 enrolled5 locationsNCT05603702
Recruiting
Phase 1
Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis
Chronic PainChronic Pancreatitis
VA Office of Research and Development40 enrolled1 locationNCT05925036
Recruiting
Phase 1
Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling
Chronic Pain
University of Minnesota30 enrolled1 locationNCT07103135
Recruiting
Phase 1Phase 2
ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
Chronic PainOpioid Withdrawal
Medical University of South Carolina240 enrolled1 locationNCT06442566
Recruiting
Phase 1
A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.
Post-herpetic neuralgiaPainChronic Pain+4 more
iN Therapeutics Co., Ltd.64 enrolled1 locationNCT06218784
Recruiting
Phase 1
A Phase I, Randomized, Double-blind, Placebo-controlled, Single-Ascending-Dose (SAD) Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of XG2002 Oral Administration in Healthy Adult Volunteers
Acute and Chronic Pain
Xgene Pharmaceutical Pty Ltd32 enrolled1 locationACTRN12624000245594
Completed
Phase 1
A Phase 1 study to evaluate Safety, Tolerability and Pharmacokinetics of Ultramicronized-Palmitoylethanolamide (PEA) in Healthy Subjects.
Chronic PainInflammation
FSD Pharma Inc.48 enrolled1 locationACTRN12620000213943
Completed
Phase 1
A Phase I Clinical Study Evaluating the Safety, Tolerability and Pharmacokinetics of HSK21542 in Healthy Volunteers
Acute and Chronic Pain
Avance Clinical72 enrolled1 locationACTRN12619001739101
Completed
Phase 1
A Phase 1, Single-Center, Randomized, Placebo-Controlled, Ascending Single-Dose Study of the Pharmacokinetics, Safety, and Tolerability of Oral XG005 in Healthy Volunteers
Chronic Pain
Xgene Pharmaceutical Inc.50 enrolled1 locationACTRN12617001330336