Phase 2 Chronic Pain Clinical Trials

18 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 118 of 18 trials

Recruiting
Phase 2

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic PainDrug Dependence of Morphine TypeSymptom, Withdrawal
University of Calgary40 enrolled1 locationNCT04939623
Recruiting
Phase 2

PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product

Chronic Pain
Staci Gruber, Ph.D.25 enrolled1 locationNCT03984565
Recruiting
Phase 2

Dronabinol as an Adjunct for Reducing Pain

Chronic PainLow Back PainBack Injuries
Christopher D. Verrico75 enrolled1 locationNCT06454669
Recruiting
Phase 2

A Mobile Intervention to Reduce Pain and Improve Health-III

Obesity and OverweightChronic PainOsteoarthritis+1 more
Wake Forest University200 enrolled1 locationNCT06623669
Recruiting
Phase 2

Combined THC and CBD for OUD and Chronic Pain

Chronic Pain
Yale University147 enrolled1 locationNCT06544291
Recruiting
Phase 2

Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

Chronic PainOsteoarthritis, Knee
Wake Forest University Health Sciences38 enrolled1 locationNCT04427709
Recruiting
Phase 2

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

Chronic PainOpioid Dependence
University of British Columbia10 enrolled1 locationNCT05585229
Recruiting
Phase 1Phase 2

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain

Chronic PainOpioid Withdrawal
Medical University of South Carolina240 enrolled1 locationNCT06442566
Recruiting
Phase 2

From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects

Chronic Pain
Massachusetts General Hospital180 enrolled3 locationsNCT05661903
Recruiting
Phase 2

Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)

Chronic PainTreatment Resistant Depression
Centre for Addiction and Mental Health16 enrolled1 locationNCT06518720
Recruiting
Phase 2

Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty

Post Operative PainChronic PainKnee Pain Chronic
University Health Network, Toronto300 enrolled3 locationsNCT06123715
Recruiting
Phase 2

The Role of Brain Dopamine in Chronic Pain

Chronic Pain
University of Rochester10 enrolled1 locationNCT05285683
Recruiting
Phase 2

Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)

Chronic PainLow Back Pain
Evon Medics LLC220 enrolled2 locationsNCT06671132
Recruiting
Phase 2

Pilot Study: Impact of Biomarker-Guided Dietary Supplementation on Quality-of-Life Measures in Subjects With Chronic Pain

Chronic Pain
Ethos Research & Development75 enrolled1 locationNCT06247813
Recruiting
Phase 2

Palmitoylethanolamide for Chronic Inflammatory Pain Conditions

Chronic Pain
Navy Medical Center San Diego80 enrolled1 locationNCT06273462
Recruiting
Phase 2

Intravenous Lidocaine on Chronic Pain in Patients Undergoing Hepatectomy

Postoperative Chronic Pain
West China Hospital260 enrolled1 locationNCT05492669
Recruiting
Phase 2Phase 3

Preoperative Paravertebral Block in Cancer Surgery of the Lung

Thoracic NeoplasmChronic Pain Post-ProceduralAcute Post-thoracotomy Pain+1 more
Guy's and St Thomas' NHS Foundation Trust100 enrolled1 locationNCT04209868
Active
Phase 2Phase 3

Does an infusion of lidocaine, around the time of breast surgery, reduce the chance of ongoing pain in the site of surgery after 6 months?

Breast CancerChronic Pain
Royal Perth Hospital150 enrolled3 locationsACTRN12618000463279