Cognitive Disorder Clinical Trials

79 recruitingLast updated: July 25, 2026

There are 79 actively recruiting cognitive disorder clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3. Top locations include Nice, France, Toronto, Ontario, Canada, Beijing, China. Updated daily from ClinicalTrials.gov.


Cognitive Disorder Trials at a Glance

79 actively recruiting trials for cognitive disorder are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 39 trials, with the heaviest enrollment activity in Nice, Toronto, and Beijing. Lead sponsors running cognitive disorder studies include Centre Hospitalier Universitaire de Nice, Sunnybrook Health Sciences Centre, and Xuanwu Hospital, Beijing.

Browse cognitive disorder trials by phase

Treatments under study

About Cognitive Disorder Clinical Trials

Looking for clinical trials for Cognitive Disorder? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cognitive Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cognitive Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 79 trials

Recruiting

Digital Dementia Registry Bavaria (digiDEM Bayern): a Multicentre, Prospective, Longitudinal Register Study Including People With Mild Cognitive Impairment and Dementia as Well as Their Family Caregivers

Alzheimer DiseaseVascular DementiaMild Cognitive Disorder+2 more
University of Erlangen-Nürnberg Medical School5,000 enrolled12 locationsNCT07721701
Recruiting
Not Applicable

Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study

Alzheimer DiseaseAlzheimer Disease, Early OnsetLogopenic Progressive Aphasia (LPA)+5 more
Mayo Clinic60 enrolled1 locationNCT02740634
Recruiting
Phase 2

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Not Applicable

Virtual Reality Training for Inhibitory Control in Neurocognitive Disorders

Cognitive Disorder
Centre Hospitalier Universitaire de Nice48 enrolled1 locationNCT06597591
Recruiting
Phase 2

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Mild Neurocognitive DisorderMajor Depressive DisorderHIV
National Institute of Allergy and Infectious Diseases (NIAID)186 enrolled41 locationsNCT06705478
Recruiting

POCD After Major Gynecologic Surgery

Postoperative Cognitive DysfunctionPerioperative Neurocognitive Disorder
Fatihhan Zeytun72 enrolled1 locationNCT07589348
Recruiting
Not Applicable

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

DementiaAlzheimer DiseaseCommunication Disorders+11 more
Stephanie Grasso60 enrolled3 locationsNCT05741853
Recruiting

The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy

Postoperative Neurocognitive DisorderCognitive FunctionsTotal Intravenous Anesthesia+6 more
Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital60 enrolled1 locationNCT07637357
Recruiting

Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

Metabolic DiseaseAutism Spectrum DisorderCognitive Disorder
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)19 enrolled1 locationNCT05600946
Recruiting

Evaluation of the Link Between Carotid Arterial Wall Viscosity and Major Neurocognitive Disorders

Neurocognitive DisordersAlzheimer's Disease
University Hospital, Rouen140 enrolled1 locationNCT07205003
Recruiting
Not Applicable

Brain Stimulation and Cognitive Training for MCI

Mild Neurocognitive DisorderCognitive DysfunctionMild Cognitive Impairment (MCI)+2 more
Medical University of South Carolina50 enrolled1 locationNCT07526740
Recruiting

Integration of Neurocognitive Biomarkers Into a Neuro-Oncology Clinic

Neurocognitive Disorders
Baptist Health South Florida200 enrolled1 locationNCT05504681
Recruiting
Not Applicable

Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients

Postoperative Neurocognitive DisorderInsomniaPostoperative Delirium+1 more
Massachusetts General Hospital50 enrolled1 locationNCT06375265
Recruiting
Not Applicable

Creation of an Ecological Tool Assessing Episodic Memory in Geriatrics

Memory DisordersNeurocognitive Disorders
Centre Hospitalier de Lens60 enrolled1 locationNCT05668598
Recruiting

Cognitive Disorders and Brain Pulse

Neurocognitive Disorders
University Hospital, Tours300 enrolled1 locationNCT05129150
Recruiting
Not Applicable

Endovascular Therapy Versus Best Medical Treatment for Acute Large Vessel Occlusion Stroke With Low NIHSS

Mild Neurocognitive DisorderThrombectomyAcute Ischemic Stroke
First Affiliated Hospital of Wannan Medical College264 enrolled1 locationNCT06143488
Recruiting
Not Applicable

Study to Evaluate the Efficacy and Safety of ATNC-MDD V1(TMS With Cognitive Training) in Mild Alzheimer's Dementia

DementiaBrain DiseasesCentral Nervous System Diseases+5 more
Advanced Technology & Communications180 enrolled11 locationsNCT06088121
Recruiting
Not Applicable

Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease

Deep Brain StimulationMild Cognitive ImpairmentMild Alzheimer's Disease+1 more
University of California, Los Angeles144 enrolled1 locationNCT05417555
Recruiting
Not Applicable

rTMS for Apathy Clinical Trial

DementiaAlzheimer DiseaseMild Cognitive Impairment+3 more
Sunnybrook Health Sciences Centre10 enrolled1 locationNCT05561205
Recruiting
Phase 2

Fisetin in Mild Alzheimer's Disease

Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+4 more
Sunnybrook Health Sciences Centre5 enrolled1 locationNCT07279714