Phase 3 Cognitive Impairment Clinical Trials

10 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 110 of 10 trials

Recruiting
Phase 3

Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

Cognitive ImpairmentMedulloblastoma, Childhood
Donald Mabbott140 enrolled20 locationsNCT05230758
Recruiting
Phase 3

GLP-1/GCG Dual Agonist in Type 2 Diabetes With Early Dementia (LIGHT-COG Study)

Type 2 DiabetesDementia, MildMild Cognitive Impairment
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School420 enrolled8 locationsNCT07083154
Recruiting
Phase 3

A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With Schizophrenia

Cognitive ImpairmentSchizophrenia; Psychosis
European Group for Research In Schizophrenia171 enrolled16 locationsNCT07084831
Recruiting
Phase 3

Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive Function

Subjects With Mild Cognitive Impairment (MCI) of AD, Alzheimer's Disease (AD) Dementia
JYAMS PET Research & Development Limited316 enrolled2 locationsNCT07422857
Recruiting
Phase 3

Biomarker Exploration in Aging, Cognition and Neurodegeneration

Cognitive ImpairmentCognitive DeclineAlzheimer Disease
University of California, Irvine300 enrolled1 locationNCT03860857
Recruiting
Phase 2Phase 3

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

Cognitive ImpairmentMitochondrial AlterationSchizophrenia and Related Disorders
Mclean Hospital100 enrolled3 locationsNCT06191965
Recruiting
Phase 3

Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial (Be-CLEVER)

StrokePost-stroke Cognitive Impairment (PSCI)
Fudan University3,200 enrolled1 locationNCT05976152
Terminated
Phase 3

Action To promote brain HEalth iN Adults (ATHENA) trial: a pilot feasibility study to determine the effects of blood pressure lowering treatment provided by a Triple Pill strategy for attenuation of cognitive decline in participants at risk for dementia.

Cognitive ImpairmentCognitive DysfunctionHypertension+1 more
The George Institute for Global Health200 enrolled1 locationACTRN12621000121864
Not Yet Recruiting
Phase 3

Better ways of pain management in adults with hip fractures

Cognitive ImpairmentHip Fracture Pain Management
Townsville Hospital122 enrolled3 locationsACTRN12618001884291
Recruiting
Phase 3

Vitamin D and Cognition Trial

Mild Cognitive Impairment and vitamin D (25-hydroxyvitamin D) blood concentration between 50 nmol/L and 12.5 nmol/L.
Professor Nicola Lautenschlager110 enrolled1 locationACTRN12607000321448