Phase 2 Cognitive Impairment Clinical Trials
46 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 46 trials
Recruiting
Phase 1Phase 2
rTMS to Improve Cognition in Parkinson's
Mild Cognitive ImpairmentParkinson's Disease
VA Office of Research and Development56 enrolled2 locationsNCT03836950
Recruiting
Phase 1Phase 2
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
Alzheimer DiseaseMild Cognitive Impairment (MCI)Subjective Cognitive Complaints (SCCs)
Massachusetts General Hospital40 enrolled1 locationNCT07236190
Recruiting
Phase 2
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 2
Novel Augmentation of DAOIB and Antioxidant for Early Dementia
Alzheimer DiseaseMild Cognitive Impairment
Chang Gung Memorial Hospital80 enrolled1 locationNCT06467539
Recruiting
Phase 1Phase 2
Sense4Safety Intervention
Mild Cognitive Impairment
University of Pennsylvania200 enrolled1 locationNCT07220668
Recruiting
Phase 2
Repurposing Siponimod for Alzheimer's Disease
Alzheimer DiseaseCognitive Impairment, MildMild Alzheimer Disease+1 more
St. Joseph's Hospital and Medical Center, Phoenix105 enrolled1 locationNCT06639282
Recruiting
Phase 2
Cognitive Remediation Intervention to Prepare for Transition of Care
Cognitive ImpairmentSickle Cell DiseaseSelf Efficacy+3 more
University of Alabama at Birmingham120 enrolled1 locationNCT05336201
Recruiting
Phase 2
Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
DementiaAlzheimers DiseaseMild Cognitive Impairment Due to Alzheimer's Disease
Brigham and Women's Hospital16 enrolled1 locationNCT06489548
Recruiting
Phase 1Phase 2
The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairment
ElderlyMild Cognitive ImpairmentOverweight or Obesity
Fudan University54 enrolled1 locationNCT07395960
Recruiting
Phase 2
Senicapoc in Alzheimer's Disease
Alzheimer DiseaseMild Cognitive Impairment
University of California, Davis55 enrolled2 locationsNCT04804241
Recruiting
Phase 2
The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
FrailtyAgingMild Cognitive Impairment
UConn Health60 enrolled1 locationNCT06027554
Recruiting
Phase 1Phase 2
Living Independence Through Functional Training
Cognitive ImpairmentMobility Limitation
University of Florida10 enrolled2 locationsNCT07125378
Recruiting
Phase 2
Study of ALTO-101 in Patients With Schizophrenia
Cognitive ImpairmentSchizophrenia
Alto Neuroscience82 enrolled14 locationsNCT06502964
Recruiting
Phase 2
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial
Mild Cognitive Impairment (MCI)Cognitive Training
Columbia University240 enrolled4 locationsNCT06601933
Recruiting
Phase 2
A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia
Cognitive Impairment Associated With Schizophrenia (CIAS)
Kynexis B.V.150 enrolled13 locationsNCT07191483
Recruiting
Phase 2Phase 3
MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
Cognitive ImpairmentMitochondrial AlterationSchizophrenia and Related Disorders
Mclean Hospital100 enrolled3 locationsNCT06191965
Recruiting
Phase 2
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
Sleep DisturbanceAMCI - Amnestic Mild Cognitive Impairment
Johns Hopkins University100 enrolled1 locationNCT05282550
Recruiting
Phase 2
Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients
Post-stroke Cognitive Impairment
Simcere Pharmaceutical Co., Ltd226 enrolled21 locationsNCT06315231
Recruiting
Phase 2
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
Breast CancerBreast Cancer Stage IBreast Cancer Stage II+5 more
UNC Lineberger Comprehensive Cancer Center90 enrolled1 locationNCT06727773
Recruiting
Phase 2
Rapamycin - Effects on Alzheimer's and Cognitive Health
Alzheimer DiseaseMild Cognitive Impairment
The University of Texas Health Science Center at San Antonio40 enrolled1 locationNCT04629495