Phase 3 Coronary Artery Clinical Trials

21 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 21 trials

Recruiting
Phase 2Phase 3

Canagliflozin Targeting Vascular Inflammation

Coronary Artery DiseaseDiabetes Type 2
Ottawa Heart Institute Research Corporation24 enrolled1 locationNCT05427084
Recruiting
Phase 3

Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction

Coronary Artery DiseaseAcute Myocardial Infarction (AMI)Coronary Atherosclerosis of Native Coronary Artery
ECRI bv332 enrolled1 locationNCT07276282
Recruiting
Phase 3

Comparison of Diagnostic Accuracy Between XTR004 PET MPI and the Composite Index of Quantitative Coronary Angiography (QCA) and Fractional Flow Reserve (FFR)

Coronary Artery Disease (CAD)
Sinotau Pharmaceutical Group395 enrolled5 locationsNCT07439133
Recruiting
Phase 3

RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)

Coronary Artery Disease
MedTrace Pharma A/S215 enrolled14 locationsNCT05134012
Recruiting
Phase 3

Comparing High and lOw-dose asPirin With Dual anTIplatelet Therapy for Three Months Using prasUgrel and aSpirin Following Coronary Artery Bypass Grafting. (OPTIMUS-CABG Trial)

Chronic Coronary SyndromeStable Coronary Artery Disease CAD
Dolnośląskie Centrum Chorób Serca im.prof. Zbigniewa Religi MEDINET Sp. z o.o.1,703 enrolled18 locationsNCT07195149
Recruiting
Phase 3

Desflurane vs. Propofol for Cardiac Anesthesia

Coronary Artery Bypass GraftingCardiac Surgery
Xijing Hospital3,560 enrolled14 locationsNCT07116733
Not Yet Recruiting
Phase 3Phase 4

COMparative Pharmacotherapy And peRsonalised stratEgy in the management of Coronary Microvascular Dysfunction double blind randomised controlled Trial - Part 1

Angina with non obstructive coronary artery disease
Sydney Local Health District130 enrolled2 locationsACTRN12625001179426
Not Yet Recruiting
Phase 3Phase 4

COMparative Pharmacotherapy And peRsonalised stratEgy in the management of Coronary Microvascular Dysfunction double blind randomised controlled Trial - Part II

Angina with non obstructive coronary artery disease
Sydney Local Health District130 enrolled2 locationsACTRN12625001174471
Not Yet Recruiting
Phase 3

PDE-5 inhibition in Ischaemia with Non-Obstructive Coronary Arteries: a double-blinded, randomised, placebo-controlled trial (PERTINENT)

IschaemiaNon obstructive coronary artery disease
Sydney Local Health District30 enrolled1 locationACTRN12625001161415
Recruiting
Phase 3

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

Coronary Artery Disease
Weill Medical College of Cornell University600 enrolled18 locationsNCT06399692
Recruiting
Phase 3

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

Coronary Artery Disease
Weill Medical College of Cornell University600 enrolled18 locationsNCT06399705
Recruiting
Phase 3

A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque

Coronary Artery DiseaseLipidemiaPlaque, Atherosclerotic
NewAmsterdam Pharma300 enrolled1 locationNCT06305559
Recruiting
Phase 3

Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual Ischemia

Atrial Fibrillation (Paroxysmal)Coronary Artery Disease Without Residual Ischemia
Hippocration General Hospital80 enrolled3 locationsNCT05549752
Recruiting
Phase 3

Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy

Coronary Artery Disease
iVascular S.L.U.2,312 enrolled39 locationsNCT05952206
Recruiting
Phase 2Phase 3

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries

Angina PectorisMicrovascular AnginaVasospastic Angina+1 more
Stanford University150 enrolled1 locationNCT06424834
Recruiting
Phase 3

Colchicine in Belgium in Patients With Coronary Artery Disease After Percutaneous Coronary Intervention

Coronary Artery Disease
AZ Sint-Jan AV2,770 enrolled19 locationsNCT06095765
Recruiting
Phase 3

SAPT Versus DAPT in Incomplete Revascularization After CABG

Coronary Artery Disease
Campus Bio-Medico University800 enrolled1 locationNCT03789916
Active
Phase 3

Comparative effect of resuscitation with hypertonic saline versus normal saline after extracorporeal circulation during cardiovascular surgery in the Intensive Care Unit (ICU)

Crystalloid resuscitation after valve replacement surgery and coronary artery bypass surgery that underwent extracorporeal circulation
Ray Mendoza Franco102 enrolled1 locationACTRN12615000466549
Not Yet Recruiting
Phase 3

Vitamin D status in heart surgery patients and effects on clinical outcomes

Elective cardiac surgery patients requiring either or both coronary artery bypass graft or valve repair or replacement
The Alfred100 enrolled1 locationACTRN12611000516987
Recruiting
Phase 2Phase 3

LoDoCo - VRIC Low Dose Colchicine in stable coronary artery disease, Vascular Reactivity and the Inflammatory Cascade.

Coronary Artery Disease
Pfizer Cardiovascular Lipid Research Grant40 enrolled1 locationACTRN12610000397011