Phase 3 Cystic Fibrosis Clinical Trials
15 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–15 of 15 trials
Recruiting
Phase 2Phase 3
Maralixibat in Patients With Cystic Fibrosis and Constipation
Cystic FibrosisConstipation Chronic Idiopathic
Children's Hospital Los Angeles20 enrolled1 locationNCT06413368
Recruiting
Phase 3
Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated210 enrolled38 locationsNCT05422222
Recruiting
Phase 3
Assessing Tenapanor as a Treatment of CF-related Constipation.
ConstipationCystic Fibrosis
Massachusetts General Hospital25 enrolled1 locationNCT06810167
Recruiting
Phase 3
Bionic Pancreas in CFRD
Cystic Fibrosis-related Diabetes
Jaeb Center for Health Research150 enrolled16 locationsNCT06449677
Recruiting
Phase 3
Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy
Chronic Rhinosinusitis (CRS)Cystic Fibrosis (CF)
Indiana University64 enrolled1 locationNCT06996951
Recruiting
Phase 3
A Study to Assess the Efficacy and Safety of HSK31858 in Participants With Non-Cystic Fibrosis Bronchiectasis
Non-cystic Fibrosis Bronchiectasis
Haisco Pharmaceutical Group Co., Ltd.669 enrolled2 locationsNCT06660992
Recruiting
Phase 3
Tolerability and Safety of Inhaled Colistimethate Sodium (CMS) Administered Once Daily Compared to Twice Daily Dosing in Adult and Adolescent Subjects with Cystic Fibrosis and Chronic Pseudomonas Aeruginosa Lung Infection (COPILOT)
Pseudomonas aeruginosa infectionCystic Fibrosis
Spexis Australia Pty Ltd38 enrolled1 locationACTRN12624000601538
Completed
Phase 3
Saline Hypertonic in Preschoolers with Cystic Fibrosis and lung structure as measured by computed tomography (CT). SHIP-CT study.
Cystic Fibrosis
Telethon Kids Institute120 enrolled13 locationsACTRN12615001067561
Completed
Phase 3
Does exenatide improve post prandial glycaemic control in young people with cystic fibrosis related diabetes or impaired glucose tolerance?
Cystic Fibrosis with Impaired Glucose Tolerance
Jennifer Couper10 enrolled1 locationACTRN12615001029583
Completed
Phase 2Phase 3
CF-IDEA (Cystic Fibrosis - Insulin Deficiency, Early Action): Randomised controlled trial of once-daily insulin detemir in patients with cystic fibrosis and early insulin deficiency
Insulin DeficiencyCystic Fibrosis
Sydney Children's Hospital100 enrolled1 locationACTRN12611000068965
Active
Phase 3
Prevention of bronchiectasis in infants with cystic fibrosis
bronchiectasis in cystic fibrosis
Telethon Kids Institute130 enrolled8 locationsACTRN12610001072000
Active
Phase 3
Study of VX-770 in Cystic Fibrosis Subjects
Cystic Fibrosis
Vertex Pharmaceutical Incorporated200 enrolled7 locationsACTRN12610000491066
Completed
Phase 3Phase 4
The long term effect of inhaled hypertonic saline (6%) in non-cystic fibrosis bronchiectasis.
Non-cystic fibrosis bronchiechtasis
Alfred Hospital, Physiotherapy Department40 enrolled1 locationACTRN12607000367448
Completed
Phase 3
Bi-level Ventilatory Support during exacerbations of Cystic Fibrosis
Cystic Fibrosis
SWSAHS40 enrolled1 locationACTRN12605000437662
Completed
Phase 3
Randomised 12 month trial of Non-Invasive Ventilation (NIV) with or without oxygen versus oxygen alone in treatment of sleep disordered breathing in Cystic Fibrosis
Cystic Fibrosis
SWSAHS40 enrolled1 locationACTRN12605000420640