Decompensated Cirrhosis Clinical Trials

9 recruiting

Decompensated Cirrhosis Trials at a Glance

15 actively recruiting trials for decompensated cirrhosis are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Barcelona, London, and Guangzhou. Lead sponsors running decompensated cirrhosis studies include European Foundation for Study of Chronic Liver Failure, Nanfang Hospital, Southern Medical University, and Post Graduate Institute of Medical Education and Research, Chandigarh.

Browse decompensated cirrhosis trials by phase

Treatments under study

About Decompensated Cirrhosis Clinical Trials

Looking for clinical trials for Decompensated Cirrhosis? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Decompensated Cirrhosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Decompensated Cirrhosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Phase 2

Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis

CirrhosisDecompensated Cirrhosis of LiverDecompensated Liver Cirrhosis+1 more
CAMC Health System50 enrolled1 locationNCT06764966
Recruiting
Phase 3

Personalized Long-term Human Albumin Treatment in Patients With Decompensated Cirrhosis and Ascites

Decompensated Cirrhosis and Ascites
Aleksander Krag240 enrolled12 locationsNCT05056220
Recruiting
Phase 1Phase 2

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

Liver DiseasesCirrhosis, LiverDecompensated Liver Cirrhosis+5 more
Resolution Therapeutics Limited30 enrolled14 locationsNCT06823713
Recruiting
Not Applicable

Effect of Whey Protein Versus Egg Albumen Protein Challenge on Blood Ammonia Level in Patients of Decompensated Ethanol Related Cirrhosis.

Decompensated Cirrhosis Ethanol Related
Institute of Liver and Biliary Sciences, India50 enrolled1 locationNCT07299110
Recruiting
Not Applicable

Hospital @ Home Model of Care for Cirrhosis

Decompensated Cirrhosis
Indiana University30 enrolled1 locationNCT06396897
Recruiting

Validation of New Prognostic Biomarkers in Patients With Decompensated Cirrhosis

Liver CirrhosisDecompensated Cirrhosis of Liver
European Foundation for Study of Chronic Liver Failure189 enrolled9 locationsNCT06855056
Recruiting
Not Applicable

Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival

Acute Kidney InjuryCirrhosis, LiverCirrhotic Cardiomyopathy+2 more
Post Graduate Institute of Medical Education and Research, Chandigarh260 enrolled1 locationNCT06431919
Recruiting
Phase 4

BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HE

Hepatic EncephalopathyDecompensated Cirrhosis
Post Graduate Institute of Medical Education and Research, Chandigarh336 enrolled1 locationNCT06538077
Recruiting
Phase 2

Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury

CirrhosisAcute Kidney InjuryDecompensated Cirrhosis of Liver
Giuseppe Cullaro, MD75 enrolled1 locationNCT06937307
Recruiting
Not Applicable

CirrhoCare- Using Smart-phone Technology to Enhance Care and Access to Treatment for Cirrhosis

Decompensated Cirrhosis
University College, London214 enrolled15 locationsNCT06223893
Recruiting
Phase 2

A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).

Liver CirrhosisDecompensated Cirrhosis of LiverAcute on Chronic Liver Failure (ACLF)
European Foundation for Study of Chronic Liver Failure90 enrolled9 locationsNCT05895136
Recruiting
Phase 2

Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-2)

Decompensated Cirrhosis
Beijing 302 Hospital140 enrolled7 locationsNCT05224960
Recruiting
Phase 4

Trial Comparing Conventional Antibiotic Strategies Versus Regimens Guided by Epidemiological Surveillance in Infected Patients With Cirrhosis (SURVIC_STUDY)

Bacterial InfectionsDecompensated Cirrhosis
Eva Bonfill198 enrolled1 locationNCT05783661
Recruiting

Prospective Cohort Study of Complications and Outcomes in Cirrhosis

Decompensated CirrhosisCMV ReactivationOvert Hepatic Encephalopathy
Nanfang Hospital, Southern Medical University660 enrolled1 locationNCT06374511
Recruiting
Not Applicable

Effect of IMO on Intestinal Microbiota Translocation in Cirrhosis

Decompensated Cirrhosis
Nanfang Hospital, Southern Medical University18 enrolled1 locationNCT06134544