Phase 3 Delirium Clinical Trials
22 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 22 trials
Recruiting
Phase 3
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
Delirium
Washington University School of Medicine46 enrolled1 locationNCT06969287
Recruiting
Phase 3
Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
Delirium
Massachusetts General Hospital1,800 enrolled14 locationsNCT06192615
Recruiting
Phase 3
Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium
Delirium on Emergence
Mayo Clinic400 enrolled1 locationNCT06624592
Recruiting
Phase 2Phase 3
Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy
DeliriumEpilepticsNeuroleptics
M.D. Anderson Cancer Center42 enrolled1 locationNCT05431595
Recruiting
Phase 3
Goal-Directed Sedation in Mechanically Ventilated Infants and Children
Post Traumatic Stress DisorderDeliriumCritical Illness+2 more
Vanderbilt University Medical Center372 enrolled1 locationNCT04801589
Not Yet Recruiting
Phase 3
Assessing the feasibility of non-steroidal anti-inflammatory drugs, benzodiazapines or no intervention in patients older than 60 who are having major surgery
Delirium
Royal Prince Alfred Hospital21 enrolled1 locationACTRN12625001042437
Recruiting
Phase 3
Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients
Postoperative DeliriumPreoperative Sleep Disorder
Xijing Hospital686 enrolled1 locationNCT06619912
Recruiting
Phase 3
A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain
Postoperative PainPostoperative DeliriumSpinal Fusion
University of California, San Francisco278 enrolled1 locationNCT05010148
Recruiting
Phase 3
Comparison of an Inhaled Sedation Strategy to an Intravenous Sedation Strategy in Intensive Care Unit Patients Treated With Invasive Mechanical Ventilation
Prevention of Delirium
University Hospital, Brest250 enrolled12 locationsNCT04341350
Recruiting
Phase 3
MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children
Emergence Delirium
Rigshospitalet, Denmark400 enrolled1 locationNCT05541276
Recruiting
Phase 2Phase 3
The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients
Delirium
Sultan Qaboos University240 enrolled2 locationsNCT06509191
Recruiting
Phase 3
Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery
Intensive Care Unit Delirium
University of Novi Sad200 enrolled1 locationNCT05849597
Recruiting
Phase 2Phase 3
The PREVENT AGITATION Trial II - Children ≤1 Year
Emergence Delirium
Rigshospitalet, Denmark336 enrolled1 locationNCT05091242
Recruiting
Phase 3
DExmedetomidine in Cardiac surgical Intraoperative Drug Evaluation
Delirium
University of Sydney1,100 enrolled15 locationsACTRN12623001171606
Recruiting
Phase 3
Managing Delirium with FLUvoxamine treatment in Non-Cardiac Surgical patients: a feasibility trial
Non-Cardiac SurgeryDelirium
Royal Prince Alfred Hosptial46 enrolled2 locationsACTRN12622000862741
Withdrawn
Phase 3
DeCaf-Me: Can delirium be prevented with caffeine and melatonin? A randomised, placebo-controlled trial
Spinal surgeryDelirium
Royal Prince Alfred Hospital57 enrolled1 locationACTRN12621001633875
Active
Phase 2Phase 3
Melatonin for Delirium Reduction, Resolution And Mitigation of Abnormal Arousal (MelaDRRAMAA)
Delirium
Royal Melbourne Hospital120 enrolled1 locationACTRN12619000034134
Terminated
Phase 2Phase 3
Melatonin to treat Delirium in Older People
Delirium
Alfred Health50 enrolled1 locationACTRN12617001537347
Completed
Phase 3
Melatonin vs. placebo for prevention of delirium in hospital in people with advanced cancer
Advanced CancerDelirium
University Technology Sydney220 enrolled11 locationsACTRN12616001618448
Completed
Phase 2Phase 3
A randomised trial of the pro-phylactic use of melatonin in critically ill patients to evaluate if this leads to a reduction in incidence of delirium (Pro-MEDIC study)
Delirium
Sir Charles Gairdner Hospital850 enrolled12 locationsACTRN12616000436471