Early Phase 1 Depression Clinical Trials

9 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 19 of 9 trials

Recruiting
Early Phase 1

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Early Phase 1

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

DepressionKnee Osteoarthritis
University of California, Los Angeles30 enrolled1 locationNCT06906939
Recruiting
Early Phase 1

Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study

DepressionEsketamineAdolescent+1 more
Min Su220 enrolled2 locationsNCT07247968
Recruiting
Early Phase 1

Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials

Depression, Anxiety
University of Alberta40 enrolled2 locationsNCT07014852
Recruiting
Early Phase 1

Confirmatory Efficacy Trial of Attention Bias Modification for Depression

Depression
University of Texas at Austin600 enrolled1 locationNCT06361095
Recruiting
Early Phase 1

Mood Effects of Serotonin Agonists: Depression

DepressionMajor Depressive DisorderLSD
University of Chicago48 enrolled1 locationNCT07017478
Recruiting
Early Phase 1

Probiotic Administration for Adolescent Depression

Depression
University of California, San Francisco77 enrolled1 locationNCT06898788
Recruiting
Early Phase 1

Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder

Major Depressive DisorderBipolar Depression
Massachusetts General Hospital20 enrolled1 locationNCT03748446
Recruiting
Early Phase 1

Personalized DBS Targeting for Treating Depression

Treatment Resistant Depression (TRD)
Second Affiliated Hospital, School of Medicine, Zhejiang University5 enrolled1 locationNCT06784388