Phase 4 Depression Clinical Trials
27 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 27 trials
Recruiting
Phase 4
TDM-Guided Treatment With SSRIs in Hospitalized Adults and Children
Depression - Major Depressive DisorderDepressive Episodes
Poznan University of Medical Sciences180 enrolled1 locationNCT07478796
Recruiting
Phase 4
Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures
Depression in Old AgeFragility Fracture
Wake Forest University Health Sciences100 enrolled1 locationNCT05851898
Recruiting
Phase 4
RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)
Unipolar DepressionBipolar Depression
Mayo Clinic120 enrolled1 locationNCT07266545
Recruiting
Phase 4
Dopaminergic Therapy for Anhedonia - 2
DepressionAnhedonia
Emory University70 enrolled1 locationNCT06075771
Recruiting
Phase 4
Esketamine With or Without Integration Therapy for Treatment-Resistant Depression
Treatment Resistant Depression (TRD)
University of Puerto Rico20 enrolled2 locationsNCT07369102
Recruiting
Phase 4
Lithium Versus Cariprazine in the Acute Phase Treatment of Bipolar Depression (DUAG9)
Depression Bipolar
Aalborg University Hospital122 enrolled1 locationNCT05913947
Recruiting
Phase 4
Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia
DepressionAnxietyFunctional Dyspepsia+1 more
Xijing Hospital of Digestive Diseases180 enrolled1 locationNCT07182890
Recruiting
Phase 4
Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia
DepressionAnxietyFunctional Dyspepsia+1 more
Xijing Hospital of Digestive Diseases180 enrolled1 locationNCT07187492
Recruiting
Phase 4
Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression
Depression - Major Depressive DisorderDepression Bipolar
Region Örebro County350 enrolled2 locationsNCT07026461
Recruiting
Phase 4
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 4
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
Depression, AnxietyDepressionAnxiety Disorders+3 more
Laureate Institute for Brain Research, Inc.165 enrolled1 locationNCT06004115
Recruiting
Phase 4
Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients
Depression
Fazaia Ruth Pfau Medical College140 enrolled2 locationsNCT06707012
Recruiting
Phase 4
Identifying and Treating Depression in the Orthopaedic Trauma Population
Depression
Wake Forest University Health Sciences100 enrolled1 locationNCT05976347
Recruiting
Phase 4
Optimal Electrical Stimulus During Electroconvulsive Therapy
Depression BipolarDepressive Disorder, Major
Region Örebro County800 enrolled1 locationNCT04057378
Recruiting
Phase 4
Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression
Treatment Resistant Depression
The George Institute162 enrolled6 locationsNCT06278779
Recruiting
Phase 4
Establishing Mobile Transcranial Magnetic Stimulation
Treatment Resistant Major Depression
Medical University of South Carolina30 enrolled1 locationNCT06748209
Recruiting
Phase 4
Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments
ConstipationPostoperative ComplicationsVomiting+2 more
Kaohsiung Veterans General Hospital.90 enrolled1 locationNCT06777758
Recruiting
Phase 4
Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT
DepressionECT
Medical University of Vienna100 enrolled1 locationNCT05655754
Recruiting
Phase 4
Examining the Effects of Estradiol on Neural and Molecular Response to Reward
DepressionAnhedoniaPsychosis
University of North Carolina, Chapel Hill103 enrolled1 locationNCT05282277
Recruiting
Phase 4
ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression
Treatment Resistant DepressionKetamine
University of Saskatchewan62 enrolled1 locationNCT03272698