Phase 2 Depression Clinical Trials

75 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 75 trials

Recruiting
Phase 2

ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression

Depression
Stanford University162 enrolled2 locationsNCT06408246
Recruiting
Phase 2

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

Advanced CancerDepression, AnxietyPsilocybin-Assisted Psychotherapy
M.D. Anderson Cancer Center30 enrolled1 locationNCT06200155
Recruiting
Phase 2

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

CancerDepressionAnxiety
M.D. Anderson Cancer Center20 enrolled1 locationNCT06801041
Recruiting
Phase 2

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

DepressionAnxietyDysautonomia+9 more
University of California, Los Angeles75 enrolled1 locationNCT06073886
Recruiting
Phase 2

Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression

DepressionSuicide
VA Eastern Colorado Health Care System472 enrolled1 locationNCT06375083
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Phase 2

Family Acceptance Project Online (Pilot RCT)

DepressionAnxietyDrug Use+6 more
University of Michigan180 enrolled1 locationNCT06839859
Recruiting
Phase 2

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Lung Non-Small Cell CarcinomaUnipolar Depression
Alan Davis10 enrolled1 locationNCT07216404
Recruiting
Phase 2

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

Treatment Resistant Depression
atai Therapeutics, Inc.142 enrolled42 locationsNCT06524830
Recruiting
Phase 2

Clinical Trial of TJ0113 Capsules in the Treatment of Patients With Depressive Disorder

Depression
Hangzhou PhecdaMed Co., Ltd.150 enrolled1 locationNCT07018245
Recruiting
Phase 1Phase 2

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)

DepressionSequestra
First Affiliated Hospital of Chongqing Medical University520 enrolled1 locationNCT05814640
Recruiting
Phase 2

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

Depression, AnxietyStressBipolar I Disorder
Mclean Hospital40 enrolled1 locationNCT05837104
Recruiting
Phase 2

Study of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in Adults

Bipolar Disorder Depression
Autobahn Therapeutics, Inc.35 enrolled15 locationsNCT06869187
Recruiting
Phase 2

Allopregnanolone (Zuranolone) in Post-stroke Depression

Post-stroke Depression
Duke University6 enrolled1 locationNCT06759558
Recruiting
Phase 2

Neurobiology of Suicide

DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 2

Clinical Trial to Investigate the Safety and Efficacy of Two Dexamfetamine Sulfate Formulations in Adults With ADHD and Moderate to Severe Depression

Depression - Major Depressive DisorderAttention Deficit Hyperactivity Disorder (ADHD)
Prof. Dr. Frank Behrens105 enrolled2 locationsNCT06967857
Recruiting
Phase 2

Antidepressant Effects of Nitrous Oxide

Major Depressive DisorderTreatment Resistant Depression
University of Chicago172 enrolled2 locationsNCT05357040
Recruiting
Phase 1Phase 2

Personalized Ultrasonic Brain Stimulation for Depression (R61)

Depression - Major Depressive DisorderMajor Depressive EpisodeTreatment-Resistant Major Depressive Disorder
Brian Mickey30 enrolled1 locationNCT06902298
Recruiting
Phase 2Phase 3

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

DepressionAnxietyInflammation+9 more
Cedars-Sinai Medical Center150 enrolled1 locationNCT05552053
Recruiting
Phase 2

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

DepressionChronic Low-back Pain
VA Office of Research and Development44 enrolled1 locationNCT06419439