Depressive Disorder Clinical Trials in Boston, Massachusetts
31 recruitingBoston, Massachusetts
Showing 1–20 of 31 trials
Recruiting
Phase 3
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences850 enrolled87 locationsNCT06966401
Recruiting
Phase 3
Study to Assess the Safety and Effectiveness of NMRA-335140-501
Major Depressive Disorder
Neumora Therapeutics, Inc.1,000 enrolled178 locationsNCT06029439
Recruiting
Phase 3
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
Major Depressive Disorder
Xenon Pharmaceuticals Inc.450 enrolled42 locationsNCT07076407
Recruiting
Phase 2
A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder
Major Depressive Disorder
Sirtsei Pharmaceuticals, Inc.456 enrolled50 locationsNCT06254612
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Major Depressive Disorder (MDD)Major Depressive Disorder With Anxious Distress
Seaport Therapeutics360 enrolled45 locationsNCT07065240
Recruiting
Not Applicable
Home-Based tDCS Treatment Of Major Depressive Disorder
Major Depressive Disorder (MDD)
Sooma Medical Inc200 enrolled1 locationNCT06976697
Recruiting
Phase 2
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Major Depressive Disorder
Syndeio Biosciences, Inc164 enrolled34 locationsNCT06547489
Recruiting
Not Applicable
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
Depression - Major Depressive DisorderMental DisorderCannabis Use Disorder
Massachusetts General Hospital80 enrolled1 locationNCT06878859
Recruiting
Phase 2
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Not Applicable
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33
Major Depressive Disorder
NYU Langone Health120 enrolled3 locationsNCT05573074
Recruiting
Phase 2
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
Major Depressive Disorder
Autobahn Therapeutics, Inc.230 enrolled50 locationsNCT06633016
Recruiting
Phase 4
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
Major Depressive Disorder
Massachusetts General Hospital100 enrolled1 locationNCT05450432
Recruiting
Phase 3
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences200 enrolled10 locationsNCT06911112
Recruiting
Not Applicable
Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression
DepressionDepression - Major Depressive DisorderDepression in Adults+3 more
Massachusetts General Hospital120 enrolled1 locationNCT07082998
Recruiting
Phase 3
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences200 enrolled18 locationsNCT06786624
Recruiting
Not Applicable
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
Traumatic Brain InjurySchizophreniaSubstance Use Disorders+4 more
Massachusetts General Hospital600 enrolled1 locationNCT04296604
Recruiting
Not Applicable
Accelerated TMS for Perinatal Depression
Major Depressive DisorderPerinatal DepressionPost Partum Depression
Brigham and Women's Hospital24 enrolled1 locationNCT06968390
Recruiting
Early Phase 1
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder
Major Depressive DisorderBipolar Depression
Massachusetts General Hospital20 enrolled1 locationNCT03748446
Recruiting
Phase 2
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
InflammationDepressive Disorder, Major
Massachusetts General Hospital100 enrolled1 locationNCT06136546
Recruiting
Phase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Major Depressive Disorder
Axsome Therapeutics, Inc.350 enrolled40 locationsNCT06223880