Phase 4 Depressive Disorder Clinical Trials
27 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 27 trials
Recruiting
Phase 4
Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression
Major Depressive DisorderChronic Major Depression, Recurrent
University of Texas at Austin50 enrolled1 locationNCT05892744
Recruiting
Phase 4
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled19 locationsNCT07105111
Recruiting
Phase 4
A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression
Depressive Disorder, Treatment-Resistant
Janssen Korea, Ltd., Korea47 enrolled6 locationsNCT07053345
Recruiting
Phase 4
TDM-Guided Treatment With SSRIs in Hospitalized Adults and Children
Depression - Major Depressive DisorderDepressive Episodes
Poznan University of Medical Sciences180 enrolled1 locationNCT07478796
Recruiting
Phase 4
Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)
Major Depressive Disorder
Nova Scotia Health Authority400 enrolled7 locationsNCT05017311
Recruiting
Phase 4
The Role of mGluR5 in CBT-I
Major Depressive Disorder (MDD)
Stony Brook University42 enrolled1 locationNCT07076342
Recruiting
Phase 4
Does Semaglutide Improve Depressive Symptoms in Patients With Major Depressive Disorder and Overweight or Obesity
Major Depressive Disorder
Nordsjaellands Hospital116 enrolled1 locationNCT07136714
Recruiting
Phase 4
Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression
Depression - Major Depressive DisorderDepression Bipolar
Region Örebro County350 enrolled2 locationsNCT07026461
Recruiting
Phase 4
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
Major Depressive Disorder
Massachusetts General Hospital100 enrolled1 locationNCT05450432
Recruiting
Phase 4
Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression
Major Depressive Disorder
University of North Carolina, Chapel Hill75 enrolled1 locationNCT06610305
Recruiting
Phase 4
Clonidine to Prevent Delirium After Electroconvulsive Therapy.
Major Depressive DisorderBipolar DisorderCatatonia+1 more
Insel Gruppe AG, University Hospital Bern130 enrolled1 locationNCT04828226
Recruiting
Phase 4
PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine.
Major Depressive Disorder (MDD)
Stony Brook University14 enrolled1 locationNCT07095205
Recruiting
Phase 4
Neural Circuit Effects of Ketamine in Depression
Major Depressive Disorder
Icahn School of Medicine at Mount Sinai120 enrolled1 locationNCT06213324
Recruiting
Phase 4
Optimal Electrical Stimulus During Electroconvulsive Therapy
Depressive Disorder, Major
Region Örebro County800 enrolled1 locationNCT04057378
Recruiting
Phase 4
Aβ Dynamics in LLMD
Alzheimer DiseaseMajor Depressive Disorder
NYU Langone Health60 enrolled2 locationsNCT05004987
Recruiting
Phase 4
Personalized Indications for CBT and Antidepressants in Treating Depression
Major Depressive DisorderPersistent Depressive Disorder
Nova Scotia Health Authority80 enrolled1 locationNCT02752542
Recruiting
Phase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Major Depressive Disorder
Axsome Therapeutics, Inc.350 enrolled40 locationsNCT06223880
Recruiting
Phase 4
Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People
Major Depressive Disorder (MDD)
Medical University of Vienna120 enrolled1 locationNCT06675851
Recruiting
Phase 4
Positioning of Esketamine Treatment in the Real-world Management of Depression
Major Depressive Disorder
Royal North Shore Hospital162 enrolled1 locationNCT06103760
Recruiting
Phase 4
Non-invasive BCI and Application Verification for Depressed People
DepressionMajor Depressive DisorderBipolar Depression
Shanghai Mental Health Center400 enrolled1 locationNCT06417437