Phase 2 Diabetes Mellitus Clinical Trials
50 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 50 trials
Recruiting
Phase 2
Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus
Type II Diabetes Mellitus
Sun Pharmaceutical Industries Limited285 enrolled21 locationsNCT07282743
Recruiting
Phase 2
A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes
Type 2 Diabetes Mellitus
Hoffmann-La Roche240 enrolled51 locationsNCT07112872
Recruiting
Phase 2
A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals40 enrolled1 locationNCT07465224
Recruiting
Phase 1Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled31 locationsNCT06783309
Recruiting
Phase 1Phase 2
Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)
Type 1 Diabetes Mellitus
University of Chicago70 enrolled1 locationNCT06305286
Recruiting
Phase 2
Study to Evaluate the Safety and Feasibility of Diamyd® in Individuals at Risk for Type 1 Diabetes
PreventionDiabetes Mellitus, Type 1Autoimmune Diseases
Diamyd Medical AB16 enrolled1 locationNCT05683990
Recruiting
Phase 2
A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin
Diabetes Mellitus, Type 2
Eli Lilly and Company100 enrolled26 locationsNCT07215312
Recruiting
Phase 2
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company200 enrolled38 locationsNCT07215559
Recruiting
Phase 1Phase 2
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 2
Dapansutrile in Diabetes and Diabetes-Related Complications - Dapan-Dia
Diabetes Mellitus, Type 2
Marc Donath300 enrolled6 locationsNCT06047262
Recruiting
Phase 2
Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes
InsulinType 1 Diabetes (T1D)Glycemic Control for Diabetes Mellitus+2 more
University of Virginia40 enrolled1 locationNCT07186660
Recruiting
Phase 1Phase 2
Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes
Diabetes Mellitus, Type 1
City of Hope Medical Center20 enrolled1 locationNCT03746769
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled2 locationsNCT06845202
Recruiting
Phase 1Phase 2
Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes
Diabetes Mellitus, Type 1Type 1 Diabetes
Creative Medical Technology Holdings Inc18 enrolled1 locationNCT05626712
Recruiting
Phase 2
FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)
Type 1 Diabetes Mellitus
Sanofi192 enrolled80 locationsNCT06111586
Recruiting
Phase 2
Aleniglipron Phase 2 in Type 2 Diabetes Mellitus
ObesityWeight LossObese+1 more
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics50 enrolled17 locationsNCT07400588
Recruiting
Phase 2
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
Type 1 Diabetes Mellitus
Mannkind Corporation100 enrolled2 locationsNCT07224321
Recruiting
Phase 2
Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody
Diabetes Mellitus, Type 1Presymptomatic Diabetes Type 1 (Stage 1)Diabetes Mellitus, Type I
PolTREG S.A.150 enrolled8 locationsNCT06688331
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus
T2DM (Type 2 Diabetes Mellitus)
Ascletis Pharma (China) Co., Limited100 enrolled8 locationsNCT07321678
Recruiting
Phase 2
Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes
Type 1 Diabetes Mellitus
Sanofi10 enrolled11 locationsNCT06791291