Phase 3 Diabetes Mellitus Clinical Trials

39 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 39 trials

Recruiting
Phase 3

Semaglutide for Smoking Cessation in Patients With Diabetes

Diabetes Mellitus, Type 2Tobacco DependenceNicotine Addiction
Ottawa Heart Institute Research Corporation100 enrolled1 locationNCT07059377
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1152 locationsNCT07064473
Recruiting
Phase 3

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Diabetes MellitusObesityOverweight
Novo Nordisk A/S630 enrolled73 locationsNCT07533175
Recruiting
Phase 3

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Type 1 Diabetes Mellitus
Sanofi723 enrolled141 locationsNCT07088068
Recruiting
Phase 2Phase 3

Open-Label Study of Dimethyl Fumarate in Adults With Type 1 Diabetes

Type 1 Diabetes Mellitus
Nanjing Medical University96 enrolled1 locationNCT07548996
Recruiting
Phase 3

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

Obesity or OverweightType 2 Diabetes Mellitus
Hoffmann-La Roche1,600 enrolled36 locationsNCT07351058
Recruiting
Phase 3

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1
vTv Therapeutics150 enrolled58 locationsNCT06334133
Recruiting
Phase 3

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Diabetes Mellitus, Type 1
Eli Lilly and Company150 enrolled107 locationsNCT07222137
Recruiting
Phase 3

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

Diabetes Mellitus, Type 1
Eli Lilly and Company300 enrolled132 locationsNCT07222332
Recruiting
Phase 3

A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

Diabetes Mellitus, Type 1
Novo Nordisk A/S877 enrolled193 locationsNCT07076199
Recruiting
Phase 3

Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)

Diabetes MellitusAtrial Fibrillation
University of Oklahoma28 enrolled1 locationNCT05174052
Recruiting
Phase 3

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Heart FailureDiabetes Mellitus, Type 1Diabetic Nephropathies+1 more
Alessandro Doria150 enrolled19 locationsNCT06217302
Recruiting
Phase 3

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

Chronic Kidney DiseasesType 2 Diabetes Mellitus
Prokidney685 enrolled95 locationsNCT05099770
Recruiting
Phase 2Phase 3

Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction

Erectile Dysfunction With Diabetes Mellitus
Ankara City Hospital Bilkent90 enrolled1 locationNCT07480161
Recruiting
Phase 3

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
Vertex Pharmaceuticals Incorporated52 enrolled29 locationsNCT04786262
Recruiting
Phase 3

Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes

Diabetes Mellitus, Type 1
University of Colorado, Denver60 enrolled2 locationsNCT05819138
Recruiting
Phase 3

Efficacy and Safety of Berlim 25/20 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia.

Dyslipidemia Associated With Type II Diabetes Mellitus
EMS228 enrolled1 locationNCT04602754
Recruiting
Phase 3

Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus

Type 2 Diabetes Mellitus
EMS270 enrolled1 locationNCT04670666
Recruiting
Phase 2Phase 3

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction

Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 3

A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer

WoundDiabetes MellitusDiabetic Foot Ulcer+1 more
Energenesis Biomedical Co., Ltd.230 enrolled24 locationsNCT05930210