Dystonia Clinical Trials

28 recruiting

Dystonia Trials at a Glance

50 actively recruiting trials for dystonia are listed on ClinicalTrialsFinder across 6 cities in 20 countries. The largest study group is Not Applicable with 25 trials, with the heaviest enrollment activity in Boston, Miami, and London. Lead sponsors running dystonia studies include Massachusetts Eye and Ear Infirmary, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, and Boston Scientific Corporation.

Browse dystonia trials by phase

Treatments under study

About Dystonia Clinical Trials

Looking for clinical trials for Dystonia? There are currently 28 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Dystonia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Dystonia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 50 trials

Recruiting
Not Applicable

Deep Brain Stimulation Surgery for Movement Disorders

DystoniaParkinson's DiseaseEssential Tremor
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT01581580
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

Dystonia
Vima Therapeutics100 enrolled37 locationsNCT07304089
Recruiting

Vercise™ DBS Dystonia Prospective Study

Dystonia
Boston Scientific Corporation300 enrolled36 locationsNCT02686125
Recruiting

Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS

Movement DisordersParkinson DiseaseDystonia+1 more
Boston Scientific Corporation200 enrolled4 locationsNCT06553625
Recruiting

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

Parkinson DiseaseDystoniaEssential Tremor
Boston Scientific Corporation5,000 enrolled19 locationsNCT03664609
Recruiting

An Observational Study of Individuals With Isolated Dystonia

Isolated/Primary Dystonia That Affects More Than One Region of the Body
Vima Therapeutics200 enrolled29 locationsNCT07111663
Recruiting

Neurosurgical Outcome Network

Trigeminal NeuralgiaHydrocephalusSubarachnoid Hemorrhage+14 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta4,500 enrolled27 locationsNCT06724029
Recruiting

Multimodal Investigation of Cortico-Basal Ganglia-Thalamo-Cortical Network Dynamics in Dystonic Patients With Deep Brain Stimulation

Dystonia
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta15 enrolled1 locationNCT06716983
Recruiting
Not Applicable

Cortical-Basal Ganglia Speech Networks

Parkinson DiseaseDystoniaEssential Tremor
Massachusetts General Hospital80 enrolled1 locationNCT04286308
Recruiting
Not Applicable

Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

Laryngeal Dystonia
University of Minnesota20 enrolled1 locationNCT07443891
Recruiting

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

EpilepsyMovement DisordersNeurologic Disorder+7 more
Boston Children's Hospital500 enrolled1 locationNCT06585605
Recruiting

A Multicenter Pediatric Deep Brain Stimulation Registry

Movement DisordersNeurologic DisorderCerebral Palsy+6 more
Boston Children's Hospital100 enrolled1 locationNCT06585618
Recruiting
Not Applicable

Sleep-specific DBS Therapy in Parkinson's Disease

DystoniaDeep Brain StimulationParkinson's Disease and Parkinsonism
University of Minnesota64 enrolled1 locationNCT05962489
Recruiting
Not Applicable

MRgFUS Pallidotomy for the Treatment of Task Specific Focal Hand Dystonia (TSFD)

Task-Specific Focal Dystonia
University of Maryland, Baltimore10 enrolled1 locationNCT06367608
Recruiting
Not Applicable

Effects of Neuromodulation in Laryngeal Dystonia

Focal DystoniaLaryngeal Dystonia
MGH Institute of Health Professions25 enrolled1 locationNCT05095740
Recruiting
Not Applicable

UltraSound-Guided Versus Non-Ultrasound-Guided Botulinum Toxin Injections in Cervical Dystonia [CUSTODY]

Idiopathic Cervical Dystonia
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta100 enrolled1 locationNCT07233993
Recruiting
Not Applicable

LIFUS For Neurological Disorders

EpilepsyDystoniaDeep Brain Stimulation+4 more
University Health Network, Toronto50 enrolled1 locationNCT07417280
Recruiting
Not Applicable

Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb Dystonia

Dystonia, FocalLimb DystoniaIdiopathic Dystonia+1 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta34 enrolled4 locationsNCT07168850
Recruiting
Not Applicable

tDCS for Laryngeal Dystonia

Laryngeal Dystonia
Yale University10 enrolled1 locationNCT06830174
Recruiting

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Movement DisordersParkinson DiseaseDystonia+4 more
Abbott Medical Devices1,000 enrolled48 locationsNCT04071847