Dystonia Clinical Trials

60 recruitingLast updated: June 18, 2026

There are 60 actively recruiting dystonia clinical trials across 22 countries. Studies span Not Applicable, Phase 2, Early Phase 1, Phase 1, Phase 3. Top locations include Boston, Massachusetts, United States, London, United Kingdom, Milan, Italy. Updated daily from ClinicalTrials.gov.


Dystonia Trials at a Glance

60 actively recruiting trials for dystonia are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Not Applicable with 28 trials, with the heaviest enrollment activity in Boston, London, and Milan. Lead sponsors running dystonia studies include Massachusetts Eye and Ear Infirmary, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, and Boston Scientific Corporation.

Browse dystonia trials by phase

Treatments under study

About Dystonia Clinical Trials

Looking for clinical trials for Dystonia? There are currently 31 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Dystonia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Dystonia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 60 trials

Recruiting

Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS

Movement DisordersParkinson DiseaseDystonia+1 more
Boston Scientific Corporation200 enrolled4 locationsNCT06553625
Recruiting

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

Parkinson DiseaseDystoniaEssential Tremor
Boston Scientific Corporation5,000 enrolled19 locationsNCT03664609
Recruiting

Vercise™ DBS Dystonia Prospective Study

Dystonia
Boston Scientific Corporation300 enrolled36 locationsNCT02686125
Recruiting
Not Applicable

Effect of Vibro-tactile Stimulation Intensity on Head Posture in Cervical Dystonia

cervical dystonia
University of Minnesota50 enrolled1 locationNCT07245615
Recruiting
Not Applicable

Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

Secondary DystoniaCerebral Palsy, Dyskinetic
Children's National Research Institute10 enrolled1 locationNCT06036199
Recruiting
Not Applicable

Deep Brain Stimulation Surgery for Movement Disorders

DystoniaParkinson's DiseaseEssential Tremor
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT01581580
Recruiting
Phase 2

Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia

cervical dystonia
Virginia Commonwealth University20 enrolled1 locationNCT06771323
Recruiting
Early Phase 1

Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia

Dystonia Disorder
Northwell Health10 enrolled1 locationNCT07626216
Recruiting
Not Applicable

Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia

Movement DisordersDystoniaCombined Dystonia+1 more
University Hospital, Strasbourg, France150 enrolled4 locationsNCT06999096
Recruiting
Phase 2

Zinc as an Adjunctive Therapy for Cervical Dystonia

cervical dystonia
University of Florida25 enrolled1 locationNCT07140874
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

Dystonia
Vima Therapeutics100 enrolled37 locationsNCT07304089
Recruiting
Not Applicable

Attention and Eye Movement in Parkinson's Disease

Parkinson's Disease (PD)Essential TremorDystonias
University of Nebraska138 enrolled1 locationNCT06899022
Recruiting
Phase 2

A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults

cervical dystonia
Ipsen132 enrolled44 locationsNCT06937931
Recruiting

An Observational Study of Individuals With Isolated Dystonia

Isolated/Primary Dystonia That Affects More Than One Region of the Body
Vima Therapeutics200 enrolled29 locationsNCT07111663
Recruiting

Multimodal Investigation of Cortico-Basal Ganglia-Thalamo-Cortical Network Dynamics in Dystonic Patients With Deep Brain Stimulation

Dystonia
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta15 enrolled1 locationNCT06716983
Recruiting

Neurosurgical Outcome Network

DepressionTrigeminal NeuralgiaObsessive-Compulsive Disorder+20 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta4,500 enrolled27 locationsNCT06724029
Recruiting
Not Applicable

Cortical-Basal Ganglia Speech Networks

Parkinson DiseaseDystoniaEssential Tremor
Massachusetts General Hospital80 enrolled1 locationNCT04286308
Recruiting
Phase 3

IncobotulinumtoxinA (Xeomin) to Treat Focal Hand Dystonia

focal hand dystonia
Alain Kaelin48 enrolled5 locationsNCT03977493
Recruiting

A Multicenter Pediatric Deep Brain Stimulation Registry

Movement DisordersNeurologic DisorderCerebral Palsy+6 more
Boston Children's Hospital100 enrolled1 locationNCT06585618
Recruiting
Not Applicable

Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

Laryngeal Dystonia
University of Minnesota20 enrolled1 locationNCT07443891