Essential Tremor Clinical Trials

53 recruiting

Essential Tremor Trials at a Glance

55 actively recruiting trials for essential tremor are listed on ClinicalTrialsFinder across 6 cities in 24 countries. The largest study group is Not Applicable with 34 trials, with the heaviest enrollment activity in Toronto, Boston, and Pittsburgh. Lead sponsors running essential tremor studies include Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Boston Scientific Corporation, and University of Florida.

Browse essential tremor trials by phase

Treatments under study

About Essential Tremor Clinical Trials

Looking for clinical trials for Essential Tremor? There are currently 53 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Essential Tremor trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Essential Tremor clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 55 trials

Recruiting
Not Applicable

Magnetoencephalography (MEG) Pilot Study

Essential Tremor
University of Florida10 enrolled1 locationNCT07446192
Recruiting
Not Applicable

Deep Brain Stimulation Surgery for Movement Disorders

DystoniaParkinson's DiseaseEssential Tremor
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT01581580
Recruiting

Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET)

Essential Tremor
Boston Scientific Corporation500 enrolled20 locationsNCT04032470
Recruiting

Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS

Movement DisordersParkinson DiseaseDystonia+1 more
Boston Scientific Corporation200 enrolled4 locationsNCT06553625
Recruiting

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

Parkinson DiseaseDystoniaEssential Tremor
Boston Scientific Corporation5,000 enrolled19 locationsNCT03664609
Recruiting
Not Applicable

EMBRACE Tremor BiFUS

Essential Tremor
InSightec100 enrolled6 locationsNCT06974916
Recruiting
Not Applicable

Cortical-Basal Ganglia Speech Networks

Parkinson DiseaseDystoniaEssential Tremor
Massachusetts General Hospital80 enrolled1 locationNCT04286308
Recruiting
Not Applicable

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

Parkinson's Disease (PD)Essential Tremor
Boston University Charles River Campus80 enrolled2 locationsNCT07455760
Recruiting
Not Applicable

Ultrasound Neuromodulation in Essential Tremor

Essential TremorNeuromodulation
University of California, San Francisco60 enrolled1 locationNCT06610877
Recruiting

Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease

Essential TremorEssential Tremor, Movement DisordersEssential Tremor-plus
CND Life Sciences300 enrolled1 locationNCT07428447
Recruiting
Not Applicable

LIFUS For Neurological Disorders

EpilepsyDystoniaDeep Brain Stimulation+4 more
University Health Network, Toronto50 enrolled1 locationNCT07417280
Recruiting
Not Applicable

Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential Tremor

Essential Tremor
University of Florida10 enrolled1 locationNCT04212780
Recruiting
Not Applicable

Algorithms for Programming DBS Systems for ET

Essential Tremor
University of Minnesota25 enrolled1 locationNCT03984643
Recruiting
Phase 1Phase 2

Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and Cerebellum for the Treatment of Essential Tremor.

Essential Tremor
São Paulo State University36 enrolled1 locationNCT07344194
Recruiting
Not Applicable

3-D Tractography FUS Ablation for Essential Tremor

Essential Tremor
University of North Carolina, Chapel Hill24 enrolled1 locationNCT06331052
Recruiting

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Movement DisordersParkinson DiseaseDystonia+4 more
Abbott Medical Devices1,000 enrolled48 locationsNCT04071847
Recruiting
Not Applicable

Attention and Eye Movement in Parkinson's Disease

Parkinson's Disease (PD)Essential Tremor
University of Nebraska138 enrolled1 locationNCT06899022
Recruiting
Not Applicable

Circadian Adaptive DBS in Essential Tremor

Essential Tremor
University of Florida25 enrolled1 locationNCT06635811
Recruiting
Phase 2

Proof of Concept Study on BP1.4979 Effect on Essential Tremor

Essential Tremor
Bioprojet50 enrolled14 locationsNCT07074002
Recruiting
Not Applicable

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Traumatic Brain InjuryStrokeBrain Disease+4 more
Jorge Gonzalez-Martinez60 enrolled1 locationNCT07056348