Grief Clinical Trials

23 recruitingLast updated: June 18, 2026

There are 23 actively recruiting grief clinical trials across 5 countries. Studies span Not Applicable, Phase 1, Early Phase 1, Phase 2. Top locations include Lubbock, Texas, United States, New York, New York, United States, Miami, Florida, United States. Updated daily from ClinicalTrials.gov.


Grief Trials at a Glance

23 actively recruiting trials for grief are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Lubbock, New York, and Miami. Lead sponsors running grief studies include Texas Tech University, Christopher Groot, and Centre for Palliative Care Education and Research, St Vincent's Hospital.

Browse grief trials by phase

Treatments under study

About Grief Clinical Trials

Looking for clinical trials for Grief? There are currently 19 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Grief trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Grief clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Phase 1

ACT for Individuals With MNCD and Their Care Partners

Depression in AdultsAnxiety Disorder GeneralizedGrief
Texas Tech University100 enrolled1 locationNCT07239609
Recruiting
Not Applicable

Telehealth to Reduce Mental Health in Family Caregivers

Mental Health IssueGriefBurden, Caregiver
Texas Tech University60 enrolled1 locationNCT05696704
Recruiting
Not Applicable

Prevention of Psychological Health Problems Via Integrated Operational Support

Depression, AnxietyGriefLeadership+1 more
New York University5,586 enrolled1 locationNCT06981598
Recruiting
Not Applicable

Evaluation of Grief Therapy Approaches for Bereaved Parents

CancerGriefBereavement
University of Miami415 enrolled5 locationsNCT05142605
Recruiting
Early Phase 1

Psilocybin for Prolonged Grief Disorder

Prolonged grief disorder
University of Virginia12 enrolled1 locationNCT06724289
Recruiting
Not Applicable

Improving Mental Health for Care Partners of Persons With AD/ADRD

Mental Health IssueGriefBurden, Caregiver
Texas Tech University60 enrolled1 locationNCT05334992
Recruiting
Not Applicable

Technology-supported Interventions for Prolonged Grief Disorder (PGD)

Prolonged Grief Disorder (PGD)
Universitat Jaume I141 enrolled2 locationsNCT06932120
Recruiting
Not Applicable

Cardiovascular Effects of Grieving

Cardiovascular HealthGriefEmotion
University of South Florida140 enrolled1 locationNCT07356635
Recruiting
Not Applicable

Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants

InsomniaStressDepressive Symptoms+9 more
Karolinska Institutet128 enrolled1 locationNCT06828276
Recruiting
Phase 2

A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients

TraumaCritical CareGrief+1 more
Weill Medical College of Cornell University172 enrolled3 locationsNCT05587517
Recruiting
Not Applicable

Accelerated Resolution Therapy for Early Maladaptive Grief

Grief
Mayo Clinic440 enrolled4 locationsNCT05624879
Recruiting
Not Applicable

Support for Bereaved Cancer Caregivers

CancerCaregiverGrief+1 more
Michigan State University70 enrolled1 locationNCT06662409
Recruiting
Not Applicable

Families Left Behind

Substance Use DisordersGriefGrief Disorder, Prolonged+1 more
RAND340 enrolled4 locationsNCT06854757
Recruiting
Not Applicable

A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department

Grief Disorder, Prolonged
Assistance Publique - Hôpitaux de Paris924 enrolled1 locationNCT06733974
Recruiting
Not Applicable

Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder

Prolonged grief disorder
University Hospital, Caen30 enrolled1 locationNCT06017765
Recruiting
Not Applicable

A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT

Prolonged grief disorder
Uppsala University270 enrolled2 locationsNCT06667674
Recruiting

To examine the impact of the Network-Centred Palliative Care Service Delivery Model using a digital Healthy End of Life Planning (HELP) App on end-of-life care experiences and outcomes of Australians

Age-related issuesCancerDementia+4 more
La Trobe University80 enrolled1 locationACTRN12624000450516
Recruiting
Phase 1

PARTING: Psilocybin-Assisted suppoRtive psychoTherapy IN the treatment of prolonged Grief; a phase II feasibility safety trial

Prolonged grief disorder
QIMR Berghofer Medical Research Institute15 enrolled1 locationACTRN12623000827639
Recruiting

Fertility Understanding Through Registry and Evaluation (FUTuRE Fertility): exploring the fertility-related quality of life and psychological distress in young people with cancer, their parents and aged matched controls.

Fertility-related griefFertility-related angerFertility-related distress+3 more
The Prince of Wales Foundation Grant150 enrolled1 locationACTRN12615001192572
Recruiting

The National Suicide Call Back Service Carers and Bereaved Online Counselling Pilot: A Clinical Controlled Trial.

Perceived carer burdenComplicated grief
Christopher Groot160 enrolled1 locationACTRN12612000767808