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Healthy Volunteers Clinical Trials

229 recruitingLast updated: May 21, 2026

There are 229 actively recruiting healthy volunteers clinical trials across 38 countries. Studies span Phase 1, Not Applicable, Phase 2, Early Phase 1, Phase 3, Phase 4. Top locations include Bethesda, Maryland, United States, Baltimore, Maryland, United States, Melbourne, Victoria, Australia. Updated daily from ClinicalTrials.gov.


Healthy Volunteers Trials at a Glance

229 actively recruiting trials for healthy volunteers are listed on ClinicalTrialsFinder across 6 cities in 38 countries. The largest study group is Phase 1 with 110 trials, with the heaviest enrollment activity in Bethesda, Baltimore, and Melbourne. Lead sponsors running healthy volunteers studies include Bristol-Myers Squibb, Hospices Civils de Lyon, and National Heart, Lung, and Blood Institute (NHLBI).

Browse healthy volunteers trials by phase

About Healthy Volunteers Clinical Trials

Looking for clinical trials for Healthy Volunteers? There are currently 204 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Healthy Volunteers trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Healthy Volunteers clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 229 trials

Recruiting
Phase 1

A Research Study to Evaluate the Safety of NNC1679-0001 When Given to Healthy Participants and Participants With T2DM

Diabetes Mellitus, Type 2Healthy Volunteers
Novo Nordisk A/S80 enrolled1 locationNCT07570992
Recruiting
Phase 1

A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease

stable coronary artery diseaseHealthy Volunteers
Hoffmann-La Roche196 enrolled1 locationNCT07495813
Recruiting

Children s Growth and Behavior Study

ObesityHealthy VolunteersEating Behaviors
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)1,500 enrolled1 locationNCT02390765
Recruiting
Phase 1

A Study of LAD106 in Healthy Adult Participants

Healthy Volunteers
Almirall, S.A.93 enrolled1 locationNCT07471932
Recruiting
Phase 1

Safety, Pharmacokinetics, and Pharmacodynamics of MTX-101 in Healthy Adults and Patients

Healthy VolunteersType 1 Diabetes
Mozart Therapeutics Australia Pty Ltd96 enrolled3 locationsNCT06324604
Recruiting
Phase 1

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants

Healthy Volunteers
Hoffmann-La Roche128 enrolled1 locationNCT07271693
Recruiting
Phase 1Phase 2

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Not Applicable

Neural and Psychological Mechanisms of Pain Perception

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)550 enrolled1 locationNCT02446262
Recruiting
Phase 1Phase 2

A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease

Healthy VolunteersChronic Kidney Disease
Ingenia Therapeutics INC94 enrolled5 locationsNCT07231679
Recruiting

Controls and Healthy Vasculature Initiative

Healthy VolunteersVascular And Immunologic Diseases
National Heart, Lung, and Blood Institute (NHLBI)1,000 enrolled1 locationNCT05403151
Recruiting
Phase 1

First-in-Human Single and Multiple Dose of KLA578-1 for Injection

Healthy Volunteers
Hunan Kelun Pharmaceutical Co., Ltd.48 enrolled1 locationNCT07143318
Recruiting
Not Applicable

Mechanism of Non-invasive Magnetic Stimulation

Healthy Volunteers
National Institute on Drug Abuse (NIDA)70 enrolled1 locationNCT03394066
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled22 locationsNCT06845202
Recruiting
Phase 1

A Study to Evaluate ALN-4915 in Adult Healthy Volunteers

Healthy Volunteers
Alnylam Pharmaceuticals44 enrolled1 locationNCT07535606
Recruiting
Phase 1

A Study to Evaluate ALN-4285 in Adult Healthy Volunteers

Healthy Volunteers
Alnylam Pharmaceuticals76 enrolled1 locationNCT07295717
Recruiting
Phase 1Phase 2

Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause

Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 1

A Study of B-3E07 and Forsteo® in Healthy Adult Female Participants

Healthy Volunteers
Syneos Health48 enrolled1 locationNCT07497503
Recruiting

Physical and Behavioral Traits of Overweight and Obese Adults

ObesityHealthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00428987
Recruiting
Not Applicable

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

ObesityHealthy VolunteersNormal Physiology
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)120 enrolled1 locationNCT05545306
Recruiting
Phase 1

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake

Healthy VolunteersDiet Therapy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)60 enrolled1 locationNCT04799301