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Healthy Volunteers Clinical Trials

248 recruitingLast updated: June 23, 2026

There are 248 actively recruiting healthy volunteers clinical trials across 40 countries. Studies span Phase 1, Not Applicable, Phase 2, Early Phase 1, Phase 3, Phase 4. Top locations include Bethesda, Maryland, United States, London, United Kingdom, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Healthy Volunteers Trials at a Glance

248 actively recruiting trials for healthy volunteers are listed on ClinicalTrialsFinder across 6 cities in 40 countries. The largest study group is Phase 1 with 123 trials, with the heaviest enrollment activity in Bethesda, London, and Baltimore. Lead sponsors running healthy volunteers studies include Bristol-Myers Squibb, Hospices Civils de Lyon, and AbbVie.

Browse healthy volunteers trials by phase

Treatments under study

About Healthy Volunteers Clinical Trials

Looking for clinical trials for Healthy Volunteers? There are currently 220 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Healthy Volunteers trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Healthy Volunteers clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 248 trials

Recruiting

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

DepressionHealthy VolunteersAnxiety Disorders+2 more
National Institute of Mental Health (NIMH)16,000 enrolled1 locationNCT00024635
Recruiting
Phase 1

A Research Study to Evaluate the Safety of NNC1679-0001 When Given to Healthy Participants and Participants With T2DM

Diabetes Mellitus, Type 2Healthy Volunteers
Novo Nordisk A/S58 enrolled1 locationNCT07570992
Recruiting
Phase 2

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting
Phase 2

Neurobiology of Suicide

DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 1

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake

Healthy VolunteersDiet Therapy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)60 enrolled1 locationNCT04799301
Recruiting
Not Applicable

Safety and User Experience of BP-CBB

Safety and Tolerability in Healthy Volunteers
Bactolife A/S60 enrolled1 locationNCT07628608
Recruiting
Phase 1Phase 2

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis.

Healthy VolunteersSclerodermaSystemic Sclerosis (SSc)+1 more
Prolium Bioscience, Inc44 enrolled3 locationsNCT07641634
Recruiting
Phase 1

A Study to Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy Participants

Healthy Volunteers
BeOne Medicines30 enrolled1 locationNCT07590102
Recruiting
Phase 1Phase 2

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

Healthy VolunteersAnemia, Sickle Cell
Bristol-Myers Squibb184 enrolled34 locationsNCT06481306
Recruiting
Not Applicable

Investigating the Transcutaneous vs. Transcranial Mechanisms of Trigeminal Nerve Stimulation (eTNS) Using fMRI

Healthy VolunteersfMRI ResearchNeurophysiology
Xidian University25 enrolled1 locationNCT07657260
Recruiting
Not Applicable

Electrical Nerve Stimulation During Sleep for Memory Consolidation

Healthy Volunteers (HV)Memory ConsolidationSleep Physiology
Xidian University30 enrolled1 locationNCT07658274
Recruiting

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

Healthy VolunteersFrailNon-Healthy/Non-Frail
National Institute on Aging (NIA)900 enrolled1 locationNCT02339012
Recruiting

Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members

NeoplasmsHealthy VolunteersHematologic Neoplasms
National Heart, Lung, and Blood Institute (NHLBI)6,000 enrolled1 locationNCT00071045
Recruiting

Adaptive Optics Retinal Imaging

Healthy VolunteersEye Diseases
National Eye Institute (NEI)1,000 enrolled1 locationNCT02317328
Recruiting

Controls and Healthy Vasculature Initiative

Healthy VolunteersVascular And Immunologic Diseases
National Heart, Lung, and Blood Institute (NHLBI)1,000 enrolled1 locationNCT05403151
Recruiting

Physical and Behavioral Traits of Overweight and Obese Adults

ObesityHealthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00428987
Recruiting

Imaging Techniques in MRI

HealthyHealthy VolunteersCardiac Risk Factors
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT01130545
Recruiting

Cytapheresis of Volunteer Donors

Healthy Volunteers
National Institute on Aging (NIA)10,000 enrolled1 locationNCT00104325
Recruiting
Early Phase 1

Human Milk Oligosaccharide-Based Synbiotic Supplement for Intestinal Microbiota Dysbiosis

Healthy Volunteers
National Heart, Lung, and Blood Institute (NHLBI)100 enrolled1 locationNCT06615986